Ice Recrystallization Inhibitors
Articles
2026 | Ice Recrystallization Inhibitors | Articles
Very cold but still too warm; functional characterization of transient warming events in stem cell grafts
Authors: McGregor C, Saleem AM, Ghannouchi L, Morton L, Li M, Ben RN, Pineault N
Published: Cytotherapy; 2026 (Accepted 13 November 2025; published 2026)
2025 | Ice Recrystallization Inhibitors | Articles
Impact of nucleation temperature and hydroxyethyl starch on ice crystal growth: Implications for cell viability during extreme temperature fluctuations.
Authors: Acker JP, Rahman A, William N
Published: Journal of Thermal Biology
2024 | Ice Recrystallization Inhibitors | Articles
Exposure of cryopreserved red cell concentrates to real-world transient warming events has a negligible impact on quality.
Authors: Acker JP, Clarke G, Ehsani-Moghaddam B, Osmani R, Yazdanbakhsh M, Phan C, Turner TR, Olafson C, Brandon-Coatham M, Kurach J
Published: Transfusion
2024 | Ice Recrystallization Inhibitors | Articles
Ice recrystallization inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis
Authors: Betsou F, Acker JP, Schwamborn JC, Mathieson W, Del Sol A, Ben RN, Turner TR, Kofanova O, Schmitt M, Okawa S, Mommaerts K
Published: Stem Cell Research
2023 | Ice Recrystallization Inhibitors | Articles
Engineered Compounds to Control Ice Nucleation and Recrystallization
Authors: Ben R, Acker JP, Mangan S, William N
Published: Annual Review of Biomedical Engineering
2023 | Ice Recrystallization Inhibitors | Articles
Improved cryopreservation of human induced pluripotent stem cell (iPSC) and iPSC derived neurons using ice-recrystallization inhibitors.
Authors: Jezierski A, Ben R, Tauskela J S, Sandhu J, Hewitt M, Aylsworth A, Baumann E, Chopra K, Huang J, lasmar S
Published: Stem Cells
2023 | Ice Recrystallization Inhibitors | Articles
Probing the Mechanism of Action of Small-Molecule Ice Recrystallization Inhibitors Using Proton Nuclear Magnetic Resonance Relaxation.
Authors: Ben R, Bordenave N, D’Costa AS, McMunn L
Published: The Journal of Physical Chemistry Letters
2023 | Ice Recrystallization Inhibitors | Articles
Taking lessons from nature to improve cell therapy cryopreservation
Authors: and Acker JP, Coatham M, William N
Published: Cell and Gene Therapy Insights
2022 | Ice Recrystallization Inhibitors | Articles
First Report of Successful Laser Warming for Frozen Gonadal Tissues and Oocytes in the Domestic Cat Model
Authors: Comizzoli P, Hagedorn M, Daly J, Ben R, Acker JP, Nagashima J, Rowlison T
Published: Biopreservation and Biobanking
2021 | Ice Recrystallization Inhibitors | Articles
Investigating the Solubility and Activity of a Novel Class of Ice Recrystallization Inhibitors
Authors: Ben RN, Newell K, Ampaw AA
Published: Processes
2020 | Ice Recrystallization Inhibitors | Articles
Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation.
Authors: Johnson L, Marks DC, Padula MP, Acker JP, Ben R, Waters L
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Control of ice recrystallization in liver tissues using small molecule carbohydrate derivatives.
Authors: Acker JP, William N
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate inhibitors.
Authors: Acker JP, William N
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment.
Authors: Pineault N, Ben RN, Doxtator E, Manesia JK, Adam MK, Jahan S
Published: Transfusion
2020 | Ice Recrystallization Inhibitors | Articles
The efficacy of ice recrystallization inhibitors in rat lung cryopreservation using a low-cost technique for ex vivo subnormothermic lung perfusion
Authors: Nagendran J, Acker JP, Himmata S, Lautner L
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Transient loss in membrane integrity following intracellular ice formation in dimethyl sulfoxide-treated hepatocyte and endothelial cell monolayers.
Authors: Acker JP, William N
Published: Cryobiology
2019 | Ice Recrystallization Inhibitors | Articles
Modulating intracellular ice growth with cell permeating small molecule ice recrystallization inhibitors.
Authors: Ben RN, Meyer JE, Briard JG, Acker JP, Poisson JS
Published: Langmuir
2017 | Ice Recrystallization Inhibitors | Articles
Hydroxyethyl starch supplemented with ice recrystallization inhibitors greatly improves cryopreservation of human red blood cells.
Authors: Ben R, Acker JP, Turner TR, Briard J, Poisson J
Published: BioProcessing Journal
2016 | Ice Recrystallization Inhibitors | Articles
O-Aryl-glycoside ice recrystallization inhibitors as novel cryo-protectants – A structure-function study.
Authors: Ben R, Acker JP, Inada T, Doshi M, Alteen M, Koyama T, Turner TR, Mancini R, Capicciotti C
Published: ACS Omega
2016 | Ice Recrystallization Inhibitors | Articles
QSAR accelerated discovery of potent ice recrystallization inhibitors.
Authors: Ben RN, Woo TK, De Luna P, Fernandez M, Briard JG
Published: Scientific Reports
2016 | Ice Recrystallization Inhibitors | Articles
Small molecule ice recrystallization inhibitors mitigate cellular damage during freezing, transient warming and thawing.
Authors: Ben RN, Acker JP, Turner TR, Poisson JS, Briard JG
Published: Scientific Reports
2016 | Ice Recrystallization Inhibitors | Articles
Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells.
Authors: Ben RN, Pineault N, Allan D, Chandran P, Jahan S, Briard JG
Published: ACS Omega
2015 | Ice Recrystallization Inhibitors | Articles
Inhibiting gas hydrate formation using small molecule ice recrystallization inhibitors.
Authors: Ben RN, Doshi M, Capicciotti CJ, Tonelli D
Published: RSC Advances
2015 | Ice Recrystallization Inhibitors | Articles
Quantitative analysis of the efficacy and potency of novel small molecule ice recrystallization inhibitors.
Authors: Ben RN, Keillor JW, Perley-Robertson E, Capicciotti CJ, Keillor K, Abraham S
Published: Crystal Growth & Design
2015 | Ice Recrystallization Inhibitors | Articles
Small ice recrystallization inhibitors enable freezing of human red blood cells with reduced glycerol concentrations.
Authors: Ben RN, Acker JP, Mancini RS, Turner T, Tchir JDR, Capicciotti CJ
Published: Scientific Reports
2014 | Ice Recrystallization Inhibitors | Articles
Designing ice recrystallization inhibitors: From antifreeze (glyco)proteins to small molecules.
Authors: Ben RN, Briard JG, Capicciotti CJ, Balcerzak AK
Published: RSC Advances
2010 | Ice Recrystallization Inhibitors | Articles
Assessing the ability of a short-fluorinated antifreeze glycopeptide and a fluorinated carbohydrate derivative to inhibit ice recrystallization.
Authors: Ben RN, Chaytor JL
Published: Bioorganic & Medicinal Chemistry Letters