Search Results
200 results
2023 | Abstracts
Automated production of gene-modified chimeric antigen receptor T cells using the Cocoon Platform
Authors: Trainor, Leonard, N., D., Bryan, Purpura, A., K., Middleton, K., Smith, T.
Published: Cytotherapy, 2023; 25:1349 - 1360
2012 | Articles
Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia.
Authors: Frisch B.J, Ashton J.M, Xing L, Becker M.W, Jordan C.T, Calvi L.M.
Published: Blood
2022 | Articles
Efficient Induction of Antigen-Specific CD8+ T-Cell Responses by Cationic Peptide-Based mRNA Nanoparticles
Authors: D’haese, Vanham, S., G., Aerts, Laeremans, J.L., T., den Roover, S., Allard, S.D.
Published: Pharmaceutics
September 2024 | Posters
HEMATOPOIETIC STEM/PROGENITOR CELLS (HPC-A) CRYOPRESERVATION PROCESS VALIDATION USING CRYOSTOR® CS10 FREEZE MEDIA
Authors: Bogdewic, Shahverdiani, SS, R., Ma, Cui, B., W., Tiss, Miciano, A., D., Lago, L.
Published: Cytotherapy, 2023; Volume 25, Issue 6, Supplement, Page S125
2012 | Articles
Implantation Site and Lesion Topology Determine Efficacy of a Human Neural Stem Cell Line in a Rat Model of Chronic Stroke.
Authors: Smith EJ, Modo M., Stroemer RP, Gorenkova N, Nakajima M, Crum WR, Tang E, Stevanato L, Sinden JD
Published: Stem Cells
2022 | Articles
Novel topical allogeneic bone-marrow-derived mesenchymal stem cell treatment of hard-to-heal diabetic foot ulcers: a proof of concept study
Authors: Andersen, Steeneveld, J.A., E., Kirketerp‑Møller, Rasmussen, K., A., O’Brien, Frimodt‑Møller, T., M., and Rossing, Engberg, P., S.
Published: Stem Cell Research & Therapy
September 2024 | Journal Articles
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial
Authors: Chaudhry, Forman, Wagner, Chen, Brown, Chen, Portnow, Natri, A., S.J., J.R., M., C.E., W., J., H.M., Wang, Ressler, Badie, Paul, Wang, Hibbard, Shulkin, Barish, D., J.A., B., J.A., L.D., J.C., N., M.E., D’Apuzzo, Ostberg, Kilpatrick, Starr, Rockne, Alizadeh, Aftabizadeh, M., J.R., J., R., R.C., D., M., Banovich, Aguilar, Myers-McNamara, Wong, Georges, Blanchard, Filippov, A., N.E., B., P., R.A., J., M.S.
Published: Nature Medicine, 2024; 30:1001–1012
2012 | Articles
Improve Process Uniformity and Cell Viability in Cryopreservation.
Authors: Zhou Y, Fowler Z, Cheng A, Sever R.
Published: BioProcess International
2019 | Articles
Technical Considerations in the Freezing, Low-Temperature Storage and Thawing of Stem Cells for Cellular Therapies
Authors: Charles J. Hunt
Published: Karger
September 2024 | Abstracts
Local manufacturing processes contribute to variability in human mesenchymal stromal cell expansion while growth media supplements contribute to variability in gene expression and cell function: a Biomedical Excellence for Safer Transfusion (BEST) collabo
Authors: Tanashi, Shaz, McKenna, M., B.H., D.H., Jin, Marks, Schäfer, P., D., R., Reems, Geng, Fontaine, J., H., M.J., Stroncek, Pati, Norris, D., S. for Biomedical Excellence for Safer Transfusion (BEST), P.J.
Published: Cytotherapy, 2024;26; Issue 6:531-539
2012 | Articles
Cryopreservation of adenovirus-transfected dendritic cells (DCs) for clinical use.
Authors: Gülen D, Talmadge JE., Maas S, Julius H, Warkentin P, Britton H, Younos I, Senesac J, Pirruccello SM
Published: International Immunopharmacology
2017 | Posters
Less Than 1% Variation in the Fill Accuracy of the SAFS-100 CellSeal® Semi-Automated Filling System
Authors: Chad Johnson, Ph.D. & Eric Rodenberg, Ph.D.
Published: Cook Regentec
September 2024 | Abstracts
Low molecular weight heparin decreases pro-coagulant activity in clinical MSC products
Authors: Schriner, Olson, J.B., S.D., Cox Jr, Triolo, C.S., F., Gill, B.S., Cardenas, J.C.
Published: Cytotherapy: Stromal Cell Therapy, 2024;26, Issue 2:194 - 200
2012 | Articles
Evaluation of Bone Marrow-Derived MSC after Cryopreservation and Hypothermic Storage in Clinically Safe Medium.
Authors: Ginis I, Grinblat B, Shirvan MH.
Published: Tissue Engineering Part C: Methods
2012 | Abstracts
Peak serum: implications of serum supply for cell therapy manufacturing.
Authors: D. Brindley, N. Davie, E. Culme-Seymour, C. Mason, David Smith, J. Rowley
Published: Regenerative Medicine
2024 | Journal Articles
Good Manufacturing Practice-compliant human induced pluripotent stemcells: from bench to putative clinical products
Authors: Mummery, van der Valk, Wieles, Novoa, Locher, Arendzen, C.L., W., B., J.J., H., C.H., Rajaei, Rabelink, Salvador, Westra, van den Berg, B., T.J., A., I.M., C.W., Grundeken, Freund, Carlotti, Steeneveld, Raymond, E., C., F., E., K.I., Yildiz, Meij, Dijkers, Fonseca Neves, Kirkeby, A., M., P., P.F., N.
Published: Cytotherapy, 2024;26:556-566
2012 | Articles
Generation of human induced pluripotent stem cells from urine samples.
Authors: Zhou T, Zhuang Q, Benda C, Li Y, Bao X, Dunzinger S, Tse H, Huang Y, Grillari J, Ho J.C, Grillari-Voglauer R, Yang J, Pei D, Wang Y, Esteban M.A., Zhang Y
Published: Nature Protocols
October 2023 | Posters
A New Cryogenic Container System for Clinical Cryopreservation of Biomaterials
Authors: Sreedhar Thirumala, Nezhla Sanderson, Michael Byers, W. Scott Goebel, Erik J. Woods
Published: Cook General Biotechnology
2024 | Journal Articles
CAR-T cell expansion platforms yield distinct T cell differentiation states
Authors: S.L., Pouzolles, Song, Jin, Underwood, M., H.W., P., S., Black, Chou, Prochazkova, Somerville, M., H-C, M., R.P., Fellowes, Cheuk, Shao, Stroncek. D.F., V., A.T., L., Khan, Shi, Taylor, Traynor, J., Highfill, R., N., R.
Published: Cytotherapy, 2024;26:757-768
2012 | Articles
Phenotypic and Functional Attributes of Lentivirus-modified CD19-specific Human CD8+ Central Memory T Cells Manufactured at Clinical Scale.
Authors: Wang X, Ostberg J.R, Naranjo A, Riddell SR, Forman SJ, Brown C.E, Jensen M.C., Bautista C, Wong C.W, Chang W, Aguilar, B
Published: Journal of Immunotherapy
2017 | Posters
Review: The Industry’s Need for Closed-System Cryogenic Storage
Authors: Erik J. Woods, Ph.D., HCLD (ABB) & Sreedhar Thirumala, Ph.D.
Published: Cook Regentec
2022 | Journal Articles
Stem-like memory T cells are generated during hollow fiber perfusion- based expansion and enriched after cryopreservation in an automated modular cell therapy manufacturing process
Authors: Cunningham, Miller, A.W., M.M., Jones, M., Frank, N., Sethi, D.
Published: Cytotherapy, 2022;24:1148-1157
2013 | Articles
Human Embryonic Stem Cell Derived Mesenchymal Progenitors Express Cardiac Markers but Do Not Form Contractile Cardiomyocytes
Authors: Raynaud, Elefanty, C. M., A. G., Stanley, Halabi, E. G. and Rafii, N., A., Elliott, D. A., Pasquier, J.
Published: PLOS ONE
2005 | Abstracts
Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications
Authors: Christelle Doucet, Isabelle Ernou, Yizhou Zhang, Jean-Roch Llense, Laurent Begot, Xavier Holy, Jean-Jacques Lataillade
Published: Journal of Cellular Physiology
September 2024 | Journal Articles
CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells
Authors: Schäfer, Pennucci, Hammad, Moritz, Mosti, R., V., R., T., L., Rositzka, Cathomen, Gläser, Alzubi, Lachmann, J., T., B., J., N., Heugel, Fischer, Rhiel, Cornu, M., J., M., T.I., Lawrenz, Schambach, Chmielewski, Mussolino, C., J., A., K.O.
Published: International Journal of Molecular Sciences, 2024:25:985
2013 | Articles
BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
Authors: Lagadinou ED, Sach A, Callahan K, Rossi RM, Neering SJ, et al.
Published: Science Direct
October 2023 | Posters
A new platelet lysate alternative to serum for ex vivo transduction and expansion of human T cells
Authors: Christina Dann, PhD, Emanuele Canestrari, PhD, Steven Charlebois, PhD
Published: Cook Regentec
September 2024 | Journal Articles
Elevated fucose content enhances the cryoprotective performance of anionic polysaccharides
Authors: Freitas, Guerreiro, Moppert, F., B.M., X., Guézennec, Concórdio-Reis, J., P., Lima, Pericão, J.C., H., Silva, Martins, J.C., F.
Published: International Journal of Biological Macromolecules, 2024;261, Part 2:129577
2013 | Abstracts
Analysis of HPC and HSC post-thaw viability, clonogenic capacity, and proliferative potential after cryopreservation in comercially available media
Authors: Almulhem N, Lutzko C, Leemhuis T
Published: Cytotherapy
October 2023 | Posters
Comparison of human platelet lysate (HPL) and fetal bovine serum (FBS) for optimal culture conditions of neonatal and adult mesenchymal stem cells (MSCs)
Authors: Chris G Taylor, Ashly Watkins, BSc, BSc, Rachael N Dayment, BSc, Mohammad Z Albanna, PhD, Erik J Woods, PhD
Published: Cook Medical
September 2024 | Journal Articles
Optimized and scalable precoating-free reprogramming of human peripheral blood mononuclear cells into iPSCs
Authors: Fiacco, & Faga, E., G., Landi, S., Zasso, J., Ambrosini, C.
Published: Current Protocols, 2024;4:e979
2013 | Articles
Supercooling as a Viable Non-Freezing Cell Preservation Method of Rat Hepatocytes
Authors: Usta OB, Kim Y, Ozer S, Bruinsma BG, Lee J, Demir E, et al.
Published: PLOS ONE
2016 | Abstracts
Comparison of clinical grade human platelet lysates for cultivation of mesenchymal stromal cells from bone marrow and adipose tissue
Authors: Morten Juhl, Josefine Tratwal, Bjarke Follin, Rebekka H. Søndergaard, Maria Kirchhoff, Annette Ekblond
Published: Scandinavian Journal of Clinical and Laboratory Investigation
2024 | Journal Articles
Inosine induces stemness features in CAR-T cells and enhances potency
Authors: Gkitsas, Sandor, Asano, Klysz, Keerthi, Feldman, Freitas, N., K., K., D.D., V., S.A., K.A., Chen, Guerrero, Xu, Patel, Fowler, Leruste, Sotillo, Y., J.A., P., S., C., A., E., Mackall, Meier, Fisher, Huang, Davis, Malipatlolla, Bashti, C.L., S., C., J., K.L., M., M., Daniel, Patel, Labanieh, Satpathy, Stuani, Mata-Alcazar, J., B., S., L., A.T., L.
Published: Cancer Cell, 2024;42: Issue 2: 266-282.e8
2013 | Articles
Fibroblast cell therapy enhances initial healing in recessive dystrophic epidermolysis bullosa wounds: results of a randomized, vehicle-controlled trial
Authors: Petrof G, Martinez-Queipo M, Mellerio J, Kemp P, McGrath J
Published: British Journal of Dermatology
2018 | Articles
The ratio of ADSCs to HSC-progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem-cell therapy
Authors: Mehmet Okyay Kilinc, Boris Minev & Aladar A. Szalay, Antonio Santidrian, Ivelina Minev, Robert Toth, Dobrin Draganov, Duong Nguyen, Elliot Lander, Mark Berman
Published: Clinical and Translational Medicine
September 2024 | Journal Articles
Effect of aging on the human myometrium at single-cell resolution
Authors: Lopez-Agullo, Punzon-Jimenez, Roson, Grases, S., P., B., D., Galvez-Viedma, Badenes, Machado-Lopez, Simon, M., R., A., C., Sibai, Ferrer-Gomez, Perez-Moraga, Mas, M., C., R., A., Satorres-Perez, Porta-Pardo, Llera-Oyola, E., E., J.
Published: Nature Communications, 2024;15:945
2013 | Articles
Validation of Contrast-Enhanced MRI to Monitor Regenerative Efficacy after Cell Therapy in a Porcine Model of Convalescent Myocardial Infarction
Authors: Li, Cheng, Malliaras, Valle, Seinfeld, D., K., K., I., J., Tseliou, Marban, Luthringer, Smith, Chowdhury, E., L. and Marban, D., R. R., S., Dawkins, E., Ho, Kanazawa, Makkar, J. F., C., H., R. R., Kreke, Blusztajn, Yee, Dharmakumar, R., M., A., K.
Published: Circulation
September 2024 | Journal Articles
StemOneTM/Stempeucel®: CDSCO approved, adult human bone marrow-derived, cultured, pooled, allogenic mesenchymal stem cells for knee osteoarthritis
Authors: Gupta A.
Published: Biomedicines, 2023; 11(11):2894.
2017 | Articles
Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells
Authors: A P Lykov, N A Bondarenko, M A Surovtseva, I I Kim, O V Poveshchenko, E A Pokushalov, V I Konenkov
Published: Bulletin of Experimental Biology and Medicine
September 2024 | Journal Articles
Qualification of a flow cytometry-based method for the evaluation of in vitro cytotoxicity of GTA002 natural killer cell therapy
Authors: Raimo, Spanholtz, M., J., Zavoianu, A.G., Meijs, W., Scholten, P.
Published: Heliyon, 2024;10:e24715
2014 | Articles
Insect Cell Line Development Using Flp-Mediated Cassette Exchange Technology.
Authors: Vidigal, Alves, J., P.M., Fernandes, F., Coroadinha, A.S., Teixeira, A.P.
Published: Methods in Molecular Biology (Methods and Protocols)
2018 | Abstracts
Human platelet lysate as a media supplement for ex vivo expansion of immune cells
Authors: E. Canestrari, S. Charlebois, S. Harris
Published: Cytotherapy
2024 | Journal Articles
Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias
Authors: S.L., V., S., S., P., Selvakumar, S., S., O., S.K., S.M., Palpant, Pearson, Bennett, Leung, Gray, Wu, D., Gupta, Skelton, McArthur, Reyes, L., N.J., L., R., H.H.L., P.P., Z., Clayton, A., R.J.P., J.R., George, Pathan, Wilkie, Kotake, Hume, Chong, Chiu, Z.E., Nguyen, Hing, Barry, T., J., F., E., Y., R.D., J.J.H., H.S., Prowse, Q., A., Lu, Shah, Kizana, Marcus, Campbell, Tjahjadi, Ongtengco, Dingwall, Ni, Paterson, J., H., E., A.D., T., L., C.F.J., S., G., H., Foster, Tran, Chen, Kumar, Jeyaprakash, Turnbull, Igoor, Mulay, Kim, Grieve
Published: Nature Cardiovascular Research, 2024;3:145–165
2014 | Articles
Isolation and Expansion of Mesenchymal Stromal/Stem Cells from Umbilical Cord Under Chemically Defined Conditions
Authors: Badraiq H, Devito L, Ilic D.
Published: Methods in Molecular Biology
2018 | Articles
Human platelet lysate in mesenchymal stromal cell expansion according to a GMP grade protocol: a cell factory experience
Authors: Valentina Becherucci, Barbara Bindi, Luisa Piccini, Paola Pavan, Vanessa Cunial, Serena Casamassima, Elisa Allegro, Silvia Bisin, Stefano Ermini, Valentina Gori, Francesca Brugnolo, Francesca Gentile, Giuseppe Astori, Riccardo Ceccantini, Franco Bambi, Elena De Rienzo
Published: Stem Cell Research & Therapy
2024 | Journal Articles
The effect of human PBMCs immobilization on their Аβ42 aggregates dependent proinflammatory state on a cellular model of Alzheimer’s disease
Authors: Kot, Tigunova, K., O., Blume, Kot, Y. Shulga, Y., S., Kurbanov, R., Andriiash, H.
Published: Frontiers in Neuroscience, 2024:18:1325287
2014 | Articles
An alliance with Miltenyi Biotec in the fight for tolerance: A venture into no man's land.
Authors: Safinia N, Lombardi G, Lechler R.
Published: MACS & more
2015 | Articles
Market Assessment of Porcine Platelet Lysate for Animal Cell Culture to Replace Serum
Authors: LARS STÅLHÖS
Published: KTH Industrial Engineering and Management
September 2024 | Journal Articles
Clinically compliant cryopreservation of differentiated retinal pigment epithelial cells
Authors: Kvanta, Efstathopoulos, Baqué-Vidal, Willenbrock, Beri, A., P., L., H., N-E, Bär, Villaescusa, Saietz, Main, Reilly, F., J.C., S., H., H., Metzger, La Manno, Wrona, Petrus-Reurer, Hedenskog, H., G., A., S., M., Zhao, Lanner, Jaberi, Lederer, Moussaud-Lamodière, E., C., F., E., A.R.
Published: Cytotherapy, 2024;26:4:P340-350
2014 | Articles
Mesenchymal Stem Cells for Regenerative Therapy: Optimization of Cell Preparation Protocols
Authors: Ikebe C, Suzuki K.
Published: BioMed Research International
2021 | Videos
BioDefined Media for Next Generation Therapies
Authors: Aoife Duffy, Sean Werner
Published: Sexton Biotechnologies
September 2024 | Journal Articles
Accessible chromatin maps of inflammatory bowel disease intestine nominate cell-type mediators of genetic disease risk
Authors: Parameswaran, Wayman, Weirauch, Jurickova, S., J.A., M.T., I., Chen, Miethke, Yang, Kottyan, X., A.G., Z., L.C., Bejjani, VanDussen, Angerman, Denson, A.T., K.L., E., L.A., Parks, Dhaliwal, Bonkowski, Miraldi, E.R., L., J., E.
2014 | Articles
Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity.
Authors: Callahan KP, Jacob S, Minhajuddin M, Frontier A, Grever MR, Corbett C, Lucas DM, Lagadinou ED, Kinghorn AD, Rossi RM, Liesveld JL, Grose V, Becker MW, Balys MM, Jordan CT., Pan L
Published: Leukemia (28 February 2014)
October 2023 | Posters
A Cryopreservation System for Direct Clinical use of MSC
Authors: Sreedhar Thirumala, Evonne Fearnot, Erik J. Woods
Published: Cook General Biotechnology
September 2024 | Journal Articles
Differentiation of monocytes and polarized M1/M2 macrophages from human induced pluripotent stem cells
Authors: Park, Feldman, T.S., R.A., Bose, Hirday, D., R., Sharma, Quinn, R., R., Bharti, Jacob, K., S.P.
Published: STAR Protocols, 2024; 5:1:102827
2014 | Articles
Human-derived raw materials: controlled, consistent collection and cryopreservation enable successful manufacturing of cell-based products.
Authors: Ramos TV, Wang W, Okhovat J, McPherson G, Burger S.
Published: Cytotherapy
2018 | Articles
Evaluation of platelet lysate as a substitute for FBS in explant and enzymatic isolation methods of human umbilical cord MSCs
Authors: Sangeetha Kandoi, Praveen kumar L, Bamadeb Patra, Prasanna Vidyasekar, Divya Sivanesan, Vijayalakshmi S., Rajagopal K., Rama Shanker Verma
Published: Nature
September 2024 | Journal Articles
Process intensification in human pluripotent stem cell expansion with microcarriers
Authors: Teale, M.A., Schneider, S.L., Eibl, D., Eibl, R.
Published: Processes, 2024;12:426
2014 | Posters
Human-Derived Raw Materials: Controlled, Consistent Collections Enable Successful Manufacturing of Cell-Based Regenerative Medicine Products
Authors: Thomas V. Ramos, MD, MS, MBA, Wenshi Wang, PhD, Jacob Okhovat, Gaytha McPherson, Scott R. Burger
Published: Hema Care
2018 | Abstracts
Characterization and cost–benefit analysis of automated bioreactor-expanded mesenchymal stem cells for clinical applications
Authors: Athena L. Russell, Rebecca C. Lefavor, Abba C. Zubair
Published: Journal of AABB: Tranfusion
September 2024 | Journal Articles
A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells
Authors: Fisher, Tieu, Malipatlolla, C., V., M., Guerrero, Klysz, Sotillo, J.A., D., E., Xu, Mackall, Bjelajac, P., C.L., J.R., Quinn, Qi, Chen, P.J., L.S., C.
Published: Cell, 2024; 187:5:1278-1295.e20
2014 | Articles
In-Depth Characterisation of Retinal Pigment Epithelium (RPE) Cells Derived from Human Induced Pluripotent Stem Cells (hiPSC).
Authors: Brandl C, Wetzel CH, Zimmermann SJ, Helbiq H, Weber BH., Milenkovic VM, Rosendahl SM, Grassmann F, Milenkovic A, Hehr U, Federlin M
Published: Neuromolecular Medicine
2016 | Abstracts
Scalable Production of Human Mesenchymal Stem Cells in a Novel Bioreactor Using a Xenogenic Free Culture System
Authors: A. Meiring, I. Schneider, S. Beasley, E. Woods
Published: Cytotherapy
September 2024 | Journal Articles
Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients results in the decrease of LINE-1 methylation level
Authors: Kiudelis, Inciuraite, Kiudelis, G., R., V., Lukosevicius, Jonaitis, Steponaitiene, R., L.V., R., Ugenskiene, Kupcinskas, Raudze, R., J., O., Adamonis, Skieceviciene, Kulokiene, K., J., U.
Published: Scientific Reports, 2024;14:4456
2014 | Articles
Selective Activity of the Histone Deacetylase Inhibitor AR-42 against Leukemia Stem Cells: A Novel Potential Strategy in Acute Myelogenous Leukemia.
Authors: Guzman ML, Abdel-Wahab O, Yang N, Levine RL, Marcucci G, Sharma KK, Roboz GJ, Balys M, Hassane DC., Corbett CA, Jordan CT, Becker MW, Steidl U
Published: Molelcular Cancer Therapeutics
October 2023 | Posters
A Novel Closed System Vial with Sentinel Test Segment for Sperm Cryopreservation
Authors: Erik J. Woods, Sreedhar Thirumala, Lindsay Newton, John K. Critser
Published: Indiana University School of Medicine, University of Missouri
September 2024 | Journal Articles
Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice
Authors: Mandegar, Kozubov, Ranjbarvaziri, MacKay, Farshidfar, M.A., M., S., C.E., F., Budan, Hoey, Li, Zeng, Song, A., T., C., A., X., Xu, Yang, Van Pell, Wu, Priest, E., J., M., I., J.R., Shenwai, Grafton, Greer-Short, Argast, G., R., F., A.
Published: Nature Communications, 2024;15:1352
2019 | Abstracts
Strategies for MSC expansion and MSC-based microtissue for bone regeneration
Authors: Varitsara Bunpetch, Zhi-Yong Zhang, Xiaoan Zhang, Shan Han, Pan Zongyou, Haoyu Wu, Ouyang Hong-Wei
Published: Biomaterials
September 2024 | Journal Articles
Successful expansion and cryopreservation of human natural killer cell line NK-92 for clinical manufacturing
Authors: Kilbride, Lee, Lee, Kim, P., S., J-Y, J-H, Pyo, Iyer, Joo, Kang, K-H, R., Y., J., Kim, Li, Lee, Byun, Y., M., E.J., H., Lim, French, Byeon, Cho, B., S.M., M., Y.
Published: PLoS ONE, 2024;19:2:e0294857
2014 | Articles
Phenotypic Characteristics of Mucosally Transmitted Hiv-1
Authors: Parrish, Nicholas F.
Published: University of Pennsylvania
2017 | Posters
The Effects of Common Transient Warming Events on Post Thaw Recovery and Viability of Human Mesenchymal Stem Cells Stored in LN2 Vapour & -80°C Environments
Authors: John Fink, Sreedhar Thirumala, Stephanie Beasley, Matt Albert, Alex Meiring, Kayla Stoy, Steve Charlebois
Published: Brooks Life Science System, Cook Regentec
September 2024 | Journal Articles
The choice of ultra-low attachment plates impacts primary human and primary canine hepatocyte spheroid formation, phenotypes, and function.
Authors: Xing, Artursson, C., P., Lauschke, Kemas, V. M., A., Mickols, E., Klein, K.
Published: Biotechnology Journal, 2024;19:e2300587
2014 | Articles
Developing an Advances Therapy Medicinal Product (ATMP) for the treatment of GvHD
Authors: Antunes, Santos
Published: FCT: Departamento de Ciências da Vida
October 2023 | Posters
A closed system container for shipping non-frozen cellular therapy products for direct clinical use
Authors: Shelly Zacharias, DVM, Sreedhar Thirumala, PhD, Rachael Dayment, BSc, Matthew Shoddy, BSc
Published: Indiana University School of Medicine
September 2024 | Journal Articles
BIOSKIN: A Protocol for the Copenhagen Translational Skin Immunology Biobank and Research Programme
Authors: Løvendorf, M., Johansen, J., Skov, L.
Published: BMJ Open, 2024;14:e077207
2014 | Articles
Standardized cryopreservation of human primary cells
Authors: Ramos TV, Mathew AJ, Thompson ML, Ehrhardt RO.
Published: Current Protocalls in Cell Biology
2018 | Articles
Platelet lysate as a novel serum-free media supplement for the culture of equine bone marrow-derived mesenchymal stem cells
Authors: Maria C Naskou, Scarlett M Sumner, Anna Chocallo, Hannah Kemelmakher, Merrilee Thoresen, Ian Copland, Jacques Galipeau, John F Peroni
Published: Stem Cell Research & Therapy
September 2024 | Journal Articles
Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity
Authors: Masayuki, Periyasamy, Wei Ting Ng, Seah, Narmada, DasGupta, Sng, Mangat, Kim Aw, O., G., J., CXY, B.C., R., R., KS, P.P., Singh, Naikar, Plissonnier, Yew, Alnawaz, Khakpoor, Kaliaperumal, Chew, M., S., M-L, H.C., M.H.J, A., N., V., Yu, Ong, Ng, Levrero, Nasir, Wai, Shirgaonkar, Khine, W., K.H., H.X., M., NSBM, CLY, N., HHTW, Connolly, Owino, Chia, Lim, Au, Tay, Narayanan, di Tocco, F.C., J.E., C.O., SL, S.G., V.B., AYL, S.
Published: Journal of Hepatology, 2024;81:1:42-61
2014 | Articles
Direct Programming of Neural Progenitors into Medium Spiny Neurons by Transcription Factor Transfection
Authors: Geater, Charlene
Published: Cardiff University
2016 | Posters
The Effect of Storage Temperature and Repetitive Temperature Cycling on the Post Thaw Functionality of Human Mesenchymal Stem Cells
Authors: John Fink, Sreedhar Thirumala, Matthew Albert, Emanuele Canestrari, Kayla Mitman, Stephanie Beasley
Published: Cook Regentec
September 2024 | Journal Articles
Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22
Authors: Zafer, Sigrist, Wu, Gurnani, McComb, Kekre, Pinto, Fatehi, Faulkes, Weeratna, R.D., A., M., C., K., S., N., D.M., D., S., Rutherford, Zhu, Holt, Marcil, Gilbert, Arbabi-Ghahroudi, Yung, Ryan, Jezierski, M., Q., R.A., A., R., M., E., S., A., Huang, Nguyen, Maclean, Nelson, Aubry, Gadoury, Hay, Webb, Raphael, J., T., S., B.H., A., C., K.A., J., S., Pon, Shepherd, Chattopadhyay, Atkins, Hussack, Iqbal, Keller, Nielsen, van Faassen, H., R.A., A, A., H., G., U., B.A., J.S.
Published: Molecular Therapy Oncology, 2024;13;32:1:200775
2014 | Articles
Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells
Authors: Lu S, Feng Q, Brooks J, Lanza R., Shabrani N, Li F, Luo C, Thon, Kimbrel EA, JN, Want J, Huo H, Kim K, Thiel A, Italiano J, Machlus KR, Cho J, Kim K
Published: Stem Cell Reports
2013 | Articles
Human-derived alternatives to fetal bovine serum in cell culture
Authors: Karin Witzeneder, Andrea Lindenmair, Christian Gabriel, Katharina Höller, Denise Theiß, Heinz Redl, Simone Hennerbichler
Published: Transfusion Medicine and Hemotherapy
2024 | Journal Articles
The effect of SARS-CoV-2 infection and vaccination on Th17 and regulatory T cells in a pregnancy cohort in NYC
Authors: Stone, Gigase, de Witte, Rommel, J., FAJ, LD, AS, Flores, Janevic, Graziani, T., T., M., Perez-Rodriguez, Lieb, Castro, MM, W., J., Dolan, Bergink, Lesseur, S., V., C.
Published: Frontiers in Immunology, 2024;15:1350288
2014 | Articles
Measuring the Potency of a Stem Cell Therapeutic
Authors: Harper H, Rich I
Published: Stem Cell Protocols, Methods in Molecular Biology
2024 | Journal Articles
Micro-engineered heart tissues on-chip with heterotypic cell composition display self-organization and improved cardiac function
Authors: Passier, Cofiño-Fabres, Blauw, R., C., L., Rensen, Boonen, P.C.N., T., Schwach, Rivera-Arbeláez, V., J.M., Ribeiro, Rijpkema, M.C., M.
Published: Advanced Healthcare Materials, 2024, 2303664
2024 | Journal Articles
CD81 and CD82 expressing tumor-infiltrating lymphocytes in the NSCLC tumor microenvironment play a crucial role in T-cell activation and cytokine production
Authors: JB, Yang, BC, Na, Kim Y, Hwang, Lim, SM, K., Kim, JY, Kang, SM, Han, Lee, JH, SS, Hong, YJ, S., Jeon, Baek, MH, Kim, Kim, S., S, Pyo, MH, DK, Byeon, Lee, KH, Han, Kim, Y., Lee, CY, Cho, H., YS
Published: Frontiers in Immunology, 2024;15:1336246
2014 | Articles
High Yield Recovery of Equine Mesenchymal Stem Cells from Umbilical Cord Matrix/Wharton’s Jelly Using a Semi-automated Process
Authors: Nazari-Shafti, Bruno, Martinez, Coleman, Alt, McClure
Published: Stem Cell Protocols, Methods in Molecular Biology
2021 | Videos
Exploring the Possibilities of Flexible Automation
Authors: Sean Werner
Published: Sexton Biotechnologies
2024 | Abstracts
Phase 1, Dose Escalation, Nonrandomized, Open-Label, Clinical Trial Evaluating the Safety and Preliminary Efficacy of Allogenic Adipose-Derived Mesenchymal Stem Cells for Recurrent Glioblastoma: A Clinical Trial Protocol
Authors: Quiñones-Hinojosa, Dickson, Ramos-Fresnedo, Almeida, Szymkiewicz, A., D.W., A., J.P., E.C., Zubair, Middlebrooks, Al-Kharboosh, Chaichana, A.C., E.H., R., K.L., Trifiletti, Abarbanel, Twohy, Green, D.M., D.N., E.L., J.J., Durand, Tzeng, Basil, Sherman, W.J., N., S.Y., A.N.
Published: Neurosurgery Practice, 2023;Dec;4:e00062
2014 | Articles
Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy
Authors: Marban L, Yee K, Minamino N, Makkar RR, Malliaras K, Dawkins JF, Chowdhury S, Marban E., Kanazawa H, Duong DT, Tseliou E, Seinfeld J, Cheng K, Middleton RC, Luthringer DJ, Kharmakumar R, Ho CS, Li D, Takayama K
Published: PLoS ONE
2016 | Posters
Off the shelf cellular therapeutics: Factors to consider during cryopreservation and storage of human cells for clinical use
Authors: Erik J. Woods, Sreedhar Thirumala, Sandhya S. Badhe-Buchanan, Dominic Clarke, Aby J. Mathew
Published: Indiana University School of Medicine, Cook Regentec LLC, International Society for Cellular Therapy, Novartis Pharmaceuticals Corporation, Charter Medical Ltd, BioLife Solutions
2024 | Journal Articles
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments
Authors: Xia, Chen, Liu, B., T., R., Zhu, Lin, Deng, Y., K., J., Zhou, Ma, Zhang, M., X., Y., Lin, Zhang, Liu, Y., H., B.
Published: Molecular Cancer, 2024;23:53
2015 | Articles
Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer.
Authors: Podrazil M, Horvath R, Becht E, et al.
Published: Oncotarget
2016 | Articles
The Establishment of Efficient Methods to Culture Immunosuppressive Mesenchymal Stromal Cells from Cord Blood and Bone Marrow
Authors: Anita Laitinen
Published: Finnish Red Cross Blood Service, University of Helsinki
September 2024 | Journal Articles
Single-cell RNA sequencing analysis of vestibular schwannoma reveals functionally distinct macrophage subsets
Authors: Croft, Baruah, Monksfield, A.P., P., P., Irving, Mahony, R.I., C., Dumitriu, Marshall, I.E., J.L., Buckley, Smith, C.D., C.G.
Published: British Journal of Cancer, 2024;130:1659–1669
2015 | Posters
Scalability of Allogeneic Stem Cell Manufacturing
Authors: Kemp K, Liang L, Hampton J, Rodriguez G, Bullen C, Kharazi A
Published: Stemedica Cell Technologies
October 2023 | Posters
Scalable Xeno-Free Expansion of Human Mesenchymal Stromal Cells in a Single-Use, Vertical-Wheel Bioreactor System
Authors: Alex Meiring, Sreedhar Thirumala PhD, Steve Charlebois PhD
Published: Cook Regentec
September 2024 | Journal Articles
PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
Authors: Chen, Kang, C., B., Sui, Liu, M., Q., Huang, Chen, L., W., Wang, Gong, Y.J., Z.
Published: EMBO Rep. 2024 Apr;25(4):2015-2044
2015 | Articles
Osteolineage Notch Ligand Jagged1 Regulates Bone Homeostasis and Parathyroid Hormone-Dependent Long Term Hematopoietic Stem Cell Function
Authors: Lawal, Calvi
Published: University of Rochester
2015 | Abstracts
Human platelet lysate-its role in the cryopreservation of mesenchymal stem cells
Authors: Erik J. Woods, Sreedhar Thirumala, Chris Taylor, Brad King
Published: Cytotherapy
September 2024 | Journal Articles
Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response.
Authors: Yang, Min, Y., I.M., Jin, Vedvyas, M.M., Y., Alcaina, Y., Son, J.Y.
Published: Frontiers in Immunology, 2024;15:1355388
2015 | Articles
Safety and Feasibility for Pediatric Cardiac Regeneration Using Epicardial Delivery of Autologous Umbilical Cord Blood-Derived Mononuclear Cells Established in a Porcine Model System.
Authors: Peral SC, Burkhart HM, Oommen S, Yamada S, et al.
Published: Stem Cells Translational Medicine
2015 | Articles
Human umbilical cord blood-derived mononuclear cells improve murine ventricular function upon intramyocardial delivery in right ventricular chronic pressure overload
Authors: Oommen S, Yamada S, Peral SC, Campbell KA, Bruinsma ES, Terzic A, Nelson TJ
Published: Stem Cell Research & Therapy
2005 | Abstracts
Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications
Authors: Christelle Doucet, Isabelle Ernou, Yizhou Zhang, Jean-Roch Llense, Laurent Begot, Xavier Holy, Jean-Jacques Lataillade
Published: Journal of Cellular Physiology
September 2024 | Journal Articles
Identification of apolipoprotein B–reactive CDR3 motifs allows tracking of atherosclerosis-related memory CD4+T cells in multiple donors
Authors: Roy, P., Suthahar, S.S.A., Makings, J., Ley, K.
Published: Frontiers in Immunology, 2024;15:1302031
2015 | Articles
Sp1 and c-Myc modulate drug resistance of leukemia stem cells by regulating survivin expression through the ERK-MSK MAPK signaling pathway
Authors: Zhang et al
Published: Molecular Cancer
2015 | Abstracts
Autologous mesenchymal stromal cells to support allogeneic hematopoietic stem cell engraftment in sickle cell disease
Authors: Elizabeth Stenger, Shala Yuan, Marco Garcia, Ian B. Copland, Jacques Galipeau
Published: Cytotherapy
September 2024 | Journal Articles
Safety of repeated administration of xenogeneic human apoptotic state (Allocetra-OTS) in Sprague Dawley rats
Authors: Amor-Baroukh, Ankri, Levy, V., C., R., Sarig, Mevorach, Hershkovitz, H., D., O., Souli, Nyska, Hershkovitz, E., A., L., Reicher, Brami, B., M.
Published: Pharmaceutics. 2024 Mar 20;16(3):426
2015 | Posters
Cryopreserved hMSCs maintain comparable in vitro functional activity compared to fresh hMSCs
Authors: Farrance I, Lock LT, Baraniak P, Rowley J
Published: Rooster Bio
2017 | Articles
Comparative analyses of industrial-scale human platelet lysate preparations
Authors: Jan Pierce, Eric Benedetti, Amber Preslar, Pam Jacobson, Ping Jin, David F Stroncek, Jo-Anna Reems
Published: Transfusion
September 2024 | Journal Articles
Toward reproducible tumor organoid culture: focusing on primary liver cancer
Authors: Guo, L., Li, C., Gong, W.
Published: Frontiers in Immunology, 2024:15:1290504
2015 | Posters
Technology Transfer and Process Development for an Autologous Cell Therapy Against Multiple Sclerosis
Authors: Legutko A, Carlier V, Gaztelumendi A, Walgraffe D, et al.
Published: Masthercell
2021 | Videos
Advancements in Manufacturing, GMP and Global Supply Chain Strategies
Authors: Sean Werner, Dan Bright, John Tomtishen
Published: IQPC Car T Global Week 2021
September 2024 | Journal Articles
Optimization of the production process of clinical-grade human salivary gland organoid-derived cell therapy for the treatment of radiation-induced xerostomia in head and neck cancer
Authors: Zanten, Bruin-Jellema, J.V., A.D., Allersma, Jorritsma-Smit, D., A., Gareb, Westra, B., H., Coppes, Baanstra, R.P., M.
Published: Pharmaceutics, 2024;16,:435
2015 | Posters
Development of a Quantitative Measurement of Mesenchymal Stem Cells Explant Outgrowth from Umbilical Cord Tissue
Authors: Mathew L. Skiles, PhD, Katherine S. Brown, PhD, Heather L. Brown, MS, CGC
Published: Annual International Cord Blood Symposium
2015 | Articles
Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity
Authors: Dimitar Tasev, Michiel H. van Wijhe, Ester M. Weijers, Victor W. M. van Hinsbergh, Pieter Koolwijk
Published: Public Library of Science
September 2024 | Journal Articles
Culture and maintenance of immune cells to model innate immune status at the feto-maternal interface
Authors: Lintao, Menon, R.C.V., R., Richardson, L.S., Chapa, J., Dalmacio, L.M.M.
Published: Methods Mol Biol. 2024;2781:119-130
2015 | Articles
A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection of control virus replication after a limiting-dose heterologous SIV challenge.
Authors: Reynolds, Matthew R. ; Weiler, Andrea M.; Piaskowski, Shari M.; et al.
Published: Vaccine
2014 | Articles
Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells
Authors: Paola Ludicone, Luca Pierelli, Daniela Fioravanti, Giuseppina Bonanno, Michelina Miceli, Claudio Lavorino, Pierangela Totta, Luigi Frati, Marianna Nuti
Published: Journal of Translational Medicine
September 2024 | Journal Articles
Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair
Authors: Quejarro, Wienert, Ennis, Skowronski, Perez-Bermejo, Soros, Jain, Vijay, Kabir, B.J., B., C.L., J., J.A., V.B., A., T., S., Chew, Sales-Lee, Lahiri, Garcia, Strukov, Efagene, Partridge, Krassovsky, Wallace, G.M., J., P., A., Y.G., O., J.R., K., K.A., Yuan, Andreoletti, Shah, Treusch, Gerstenberg, Thomas, Matern, Seim, Lalisan, Y., G., M., S., T.L., J., W.M., K.L., C.D., Grogan, Catton, Silva, Dever, Hill, Veraz, Holden, Lord, D., J.L., E., B.J., D.P., K.A., M., J.K.
Published: Nature Communications, 2024;15:2625
2015 | Articles
A placebo-controlled randomised trial to assess the effect of TGF-ß1-expressing chondrocytes in patients with arthritis of the knee
Authors: Lee MC, Ha CW, Elmallah RK, Cherian JJ, Cho JJ, Kim TW, Bin SI, Mont MA
Published: The Bone & Joint Journal
2018 | Articles
Comparison of the efficacy of cryopreserved human platelet lysate and refrigerated lyophilized human platelet lysate for wound healing
Authors: Sharon Claudia Notodihardjo, Naoki Morimoto, Natsuko Kakudo, Toshihito Mitsui, Tien Minh Le, Yasuhiko Tabata, Kenji Kusumoto
Published: Regenerative Therapy
September 2024 | Journal Articles
GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes
Authors: Schweinoch, Chicoine, Chen, Uenishi, Tewari, Mueller, Saikumar-Lakshmi, D., A., T.F., G.I., R., K.T., P., Guo, Guiastrennec, Kellogg, Buckner, Repic, Cook, T., B., H., J.H., M., P.J., Zarin, James, Hunt, Rawlings, Yam, Yang, P., E., M., D.J., J.Y., S.J., Sassone-Corsi, Patel, Drow, Wickham, Landuyt, Cerosaletti, K., M., C., T., T.J., A.
Published: JCI Insight, 2024;9(6):e171844
2015 | Articles
Hair restoration surgery: challenges and solutions
Authors: Rose PT.
Published: Clinical, Cosmetic and Investigational Dermatology
2016 | Articles
Fabrication and Characterization of NanoCalcium Sulfate and Human Platelet Lysate as a Growth Factor Delivery System
Authors: Andrew Barone, Adam Morrell, Rosemary Dziak
Published: International Journal of Dentistry and Oral Health
September 2024 | Journal Articles
Intraarticular treatment with integrin α10β1-selected mesenchymal stem cells affects microRNA expression in experimental post-traumatic osteoarthritis in horses
Authors: Skovgaard, Andersen, Vonk, K., C., L.A., Lundgren-Åkerlund, Jacobsen, Walters, E., S., M., Henriksen, Bundgaard, B.L., L., Lindegaard, Berg, C., L.C.
Published: Frontiers in Veterinary Science, 2024;11:1374681
2015 | Articles
Sendai Virus-Based Reprogramming of Mesenchymal Stromal/Stem Cells from Umbilical Cord Wharton’s Jelly into Induced Pluripotent Stem Cells.
Authors: Miere, C., Devito, L., and Ilic, D.
Published: Methods In Molecular Biology
2016 | Articles
Choice of xenogenic-free expansion media significantly influences the myogenic differentiation potential of human bone marrow-derived mesenchymal stromal cells
Authors: Juliane Brun, Tanja Abruzzese, Bernd Rolauffs, Wilhelm K Aicher, Melanie L Hart
Published: Cytotherapy
2024 | Journal Articles
Single-cell RNA-sequencing of virus-specific cellular immune responses in chronic hepatitis B patients
Authors: Baumert, Hatje, Simo-Noumbissie, T.F., K., P., Kumpesa, Pelletier, Kam-Thong, N., N., T., Nilsson, Forkel, Giroud, T., M., N., Habersetzer, Saviano, F., A.
Published: Scientific Data, 2024;11:1:355
2015 | Articles
TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients.
Authors: Hossain DMS, Pal SK, Moreira D, et al.
Published: Clinical Cancer Research
2013 | Articles
Production of human platelet lysate by use of ultrasound for ex vivo expansion of human bone marrow-derived mesenchymal stromal cells
Authors: Martina Bernardi, Elena Albiero, Alberta Alghisi, Katia Chieregato, Chiara Lievore, Domenico Madeo, Francesco Rodeghiero, Giuseppe Astori
Published: Cytotherapy
2024 | Journal Articles
Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial
Authors: Csiki, Kagohara, Yarchoan, Rochestie, Yan, I., L.T., M., S., J., Cooch, Weiner, Bartha, Gane, Peters, N., D.B., G., E.J., J., Shu, Perales-Puchalt, Northcott, Marron, Connor, D.H., A., J., T.U., J.T., Fertig, Sardesai, Lyle, Perales-Linares, Jaffee, E.M., E.J., N.Y., J., R.
Published: Nature Medicine, 2024;4:1044-1053
2015 | Articles
Human Engineered Heart Muscles Engraft and Survive Long-Term in a Rodent Myocardial Infarction Model
Authors: Riegler J, Tiburcy M, Ebert A, Tzatzalos E, Raaz U, et al.
Published: Circulation Research
2015 | Articles
Scalable efficient expansion of mesenchymal stem cells in xeno free media using commercially available reagents
Authors: Neil H Riordan, Francisco Silva, Marialaura Madrigal, Amit N Patel, Jason Reneau, Kathya de Cupeiro, Natalia Jiménez, Sergio Ruiz, Nelsy Sanchez, Thomas E Ichim
Published: Journal of Translational Medicine
2024 | Journal Articles
Lentivirus-mediated BCL-XL overexpression inhibits stem cell apoptosis during ex vivo expansion and provides competitive advantage following xenotransplantation.
Authors: Zehnle, Erlacher, P.M.A., M., Wu, Y., Koleci, N., Bohler, S.
Published: International Journal Molecular Science, 2024;25:7:4105
2015 | Articles
Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells
Authors: V Chen, J Gold, J Ye, J Wu, D Hsu, P Shukla, L Couture, G Hua, D Chen, Z Lin, J Liu, J Chai
Published: Stem Cell Research
2015 | Articles
A therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement
Authors: Carlos Luzzani, Alejandra Guberman, Gabriel Neiman, María Elida Scassa, Gustavo Emilio Sevlever, Ximena Garate, Leonardo Romorini, María Questa, Santiago Gabriel Miriuka, Claudia Solari, Darío Fernandez Espinosa, Marcela García, Ana Lía Errecalde
Published: Stem Cell Research & Therapy
2024 | Journal Articles
Oral PD-L1 inhibitor GS-4224 selectively engages PD-L1 high cells and elicits pharmacodynamic responses in patients with advanced solid tumors
Authors: Dunbar, Odegard, Deva, Nazareno, P.R., J.M., S., J., Yoon, Thai, Othman, O.K., D., A.A., Ling, Ang, Lin, J., E., K.W., Lad, Waldron, Wang, L., N., A.Y.
Published: Journal for Immunotherapy of Cancer, 2024;12:4:e008547
2015 | Articles
Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy
Authors: Greene SJ, Sikora S, Epstein SE, Verkh L, Tankovich NI, Kim RJ, Gheorghiade M, Quyyumi AA, Butler J, Cole RT, Anderson AS, Wilcox JE, Skopicki HA
Published: Journal of Cardiovascular Medicine
September 2024 | Journal Articles
Can Neutrophils Prevent Nosocomial Pneumonia after Serious Injury?
Authors: Macáková K, Kaczmarek E, Itagaki K.
Published: International Journal of Molecular Sciences, 2023:24:7627
2013 | Abstracts
The effect of platelet lysate fibrinogen on the functionality of MSCs in immunotherapy
Authors: Ian B Copland, Marco A Garcia, Edmund K Waller, John D Roback, Jacques Galipeau
Published: Biomaterials
September 2024 | Journal Articles
A toxicology study of Csf2ra complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice
Authors: Cancelas, Ma, Reeves, Arumugam, Kalenda Yombo, Wessendarp, J.A., Y., L., P., D.J., M., Shima, Adams, Black, Kaiser, Carey, Sakthivel, K., M., D., A., B.C., H., Chalk, Hoskins, Imbrogno, Trapnell, Wikenheiser-Brokamp, Suzuki, C., E., M., B.C., K.A., T., Stock, Lowe-Daniels, Collins, Krischer, Lutzko, C., J., D., M., J.
Published: Molecularl Therapy Methods & Clinical Development, 2024;32:2:101213
2015 | Articles
A simple and efficient method for cryopreservation and recovery of viable Plasmodium vivax and P. falciparum sporozoites
Authors: Singh N, Barnes SJ, Jenwithisuk R, Sattabongkot J, Adams JH
Published: Parasitology International. Epub 8 Dec 2015
2013 | Abstracts
Serum-converted platelet lysate can substitute for fetal bovine serum in human mesenchymal stromal cell cultures
Authors: Mariluz P Mojica-Henshaw, Pam Jacobson, Julie Morris, Linda Kelley, Jan Pierce, Michael Boyer, Jo-Anna Reems
Published: Cytotherapy
September 2024 | Journal Articles
Age-specific nasal epithelial responses to SARS-CoV-2 infection
Authors: Pinto, Vinette, Lindeboom, Kilich, Woodall, Heywood, Cakir, Barclay, Masonou, Meyer, K.B., A., H., R.G.H., E., M.N.J., W.E., B., W., T., Yoshida, Nikolic, Moulding, Roy, Mamanova, Mehta, Cujba, Mills, Ellis, De Coppi, M., M.Z., D., S., L., P., AM., K., S., P., Butler, Polanski, C.M., McHugh, Breuer, Bolt, O’Callaghan, Worlock, Hynds, Palor, C.R., K., T.D., J., L., C., K.B., R.E., M., Cortina-Borja, Huang, Saleh, Chambers, Richardson, Zhou, Case, Teichmann, Burgoyne, T., M., N., A., R.C., L., J., K-M, S.A.
Published: Nature Microbiology, 2024;9:1293–1311
2015 | Abstracts
Intracerebral Cell Implantation: Preparation and Characterization of Cell Suspensions
Authors: Rossetti T, Nichols F, Modo M
Published: Cell Transplant
2018 | Articles
Evaluation of platelet lysate as a substitute for FBS in explant and enzymatic isolation methods of human umbilical cord MSCs
Authors: Sangeetha Kandoi, Praveen kumar L, Bamadeb Patra, Prasanna Vidyasekar, Divya Sivanesan, Vijayalakshmi S., Rajagopal K., Rama Shanker Verma
Published: Nature Scientific Reports
September 2024 | Journal Articles
Dysregulation of CD4+ and CD8+ resident memory T, myeloid, and stromal cells in steroid-experienced, checkpoint inhibitor colitis
Authors: Zhang, Yang, Kattah, He, Kushnoor, Bain, L., H., M.G., J.Y., D., J., Rao, Fong, Tsui, Oh, Kim, Shi, A.A., L., J., D.Y., Y., Y., Andersen, Combes, Shen, Mennillo, Fan, C., A.J., A., E., F., Law, Pisco, Davidson, Rusu, Cheung, A., K., A.O., B., J.
Published: Journal for ImmunoTherapy of Cancer, 2024;12:e008628
2016 | Articles
Designing a dendritic cell-based therapy for primary liver cancer
Authors: Curbishley SM, Blahova M, Adams DH
Published: MACS & more
September 2024 | Journal Articles
Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer
Authors: Feng, Shah, Zhang, M., Z., J., Li, Caligiuri, Tian, Z., M..A, L., Barr, Yu, Li, T., J., Z., Tang, Jin, H., L.
Published: Cell Stem Cell, 2024;31:6:803-817.e6
2016 | Abstracts
Transplantation of cryopreserved MSC rescues retinal ganglion cells following I/R injury
Authors: Gramlich OW, Zhu W, Burand A, Ankrum JA, et al.
Published: ARVO Journal
September 2024 | Journal Articles
DNA quantity and quality comparisons between cryopreserved and FFPE tumors from matched pan-cancer samples
Authors: Fatema, Okojie, Packer, K., J., I., Anderson, Dixon, O’Neal, D., K., N., Davis, Barrott, Burr, J., J.J., M., Kearns, Worley, B., P.
Published: Current Oncology, 2024; 31:5:2441-2452
2016 | Articles
Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions
Authors: Hoerstrup, Slamecka, Kehl, S. P. and Weber, J., D., Laurini, B., Salimova, J., L., Cinelli, McClellan, P., S., Owen, van Kelle, L., M.
Published: Cell Cycle
2024 | Journal Articles
Sorbitol destroyed intestinal microfold cells (M Cells) development through inhibition of PDE4-mediated RANKL expression
Authors: Huang, Xiang, Gong, Xie, C., L., S., S., Liang, Luo, Pan, Xu, X., M., W., W., Yang, Xu, Chen, Zhao, F., Y., H., J., Niu, Geng, Du, R., L., W.
Published: Mediators of Inflammation, 2024;7524314
2016 | Articles
Cell freezing protocol optimized for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells
Authors: Milani P, Svendsen CN, Escalante-Chong R, Fraenkel E, Shelley BC, Patel-Murray NL, Xin X, Adam M, Mandefro B, Sareen D
Published: BioRxiv Epublication
September 2024 | Journal Articles
The long noncoding RNA CCAT2 induces chromosomal instability through BOP1-AURKB signaling
Authors: Multani, Bhuvaneshwar, Shimura, Girnita, Reineke, Chen, Sen, Shimizu, Gagea, Ferracin, Knutsen, Kopetz, S., A.S., K., T., L., L.C., B., S., M., M., M., E., Liu, Parker-Thornburg, Pardini, Gusev, Ivkovic, Slaby, Huo, Dragomir, Matsuyama, Shah, Li, Oki, X., J., B., Y., T.C., O., L., M.P., T., M.Y., C., E., Fromm, Tang, Taguchi, Burks, Mimori, Cruz De los Santos, Goel, Syed, Fabris, Uetake, Ling, Ajani, B., C., A., J.K., K., M., A., M., L., H., H., J.A., Calin, Ivan, Li, Hanash, Katayama, Menter, Anfossi, Varani, Song, Bayraktar, Vasilescu, Shen, P., G.A., C., Y., S.M., H., D., S., G., S., R., C.
Published: Gastroenterology, 2020;159:2146–2195
October 2023 | Articles
Widespread Myocardial Delivery of Heart-Derived Stem Cells by Nonocclusive Triple-Vessel Intracoronary Infusion in Porcine Ischemic Cardiomyopathy: Superior Attenuation of Adverse Remodeling Documented by Magnetic Resonance Imaging and Histology
Authors: Tseliou E, Marban L, Kanazawa H, Kar S, Makkar R, Dawkins J, Marbán E, Gallet R, Kreke M, Smith R, Middleton R, Valle J
Published: PLoS One
2024 | Journal Articles
Improving cutaneous wound healing in diabetic mice using naturally derived tissue-engineered biological dressings produced under serum-free conditions
Authors: Safoine, M., Paquette, C., Gingras, G-M, Fradette, J.
Published: Stem Cells International, 2024;3601101
2016 | Articles
Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation
Authors: Turka, Guinan, Janec, L. A. and Markmann, E. C., K. J., Yuan, J., Cole, H., G. A., Oppatt, Wylie, J., W. H., Brennan, Kelner, L. L., R. H.
Published: American Journal Of Transplantation
2024 | Journal Articles
Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis
Authors: Song, Hacohen, Smith, Sharova, Thomas, Nieman, Khalili, Samanta, Y., N., N.P., T., M.F., L.T., H., N., Tantivit, Xu, Li, Tirard, Glasser, Slowikowski, Chen, Juric, J., K.H., B., A., R., K., J.H., D., Boland, Nasrallah, Jorgji, Reynolds, Ramesh, Chan, Manakongtreecheep, Eisenhaure, G.M., M., V., K.L., S., PY, K., T., Dougan, Zubiri, Pinto, Villani, Arnold, Sullivan, Sen, Pelka, K., M., L., C.J., A-C, B.Y., R.J., P.
Published: Nature Medicine, 2024;30:1349–1362
2016 | Articles
A10.08 Detailed analysis of the effect of cryopreservation on the viability and cytokine release of human synovial tissue.
Authors: de Vries M, Broeren MGA, Bennink MB, et al.
Published: Annals of the Rheumatic Diseases
September 2024 | Journal Articles
Hepatocyte size fractionation allows dissection of human liver zonation
Authors: LeCluyse, Ölander, Handin, E.L., M., N., Pedersen, Urdzik, Wegler, J.M., J., C., Vildhede, Artursson, Flörkemeier, A., P., I., Mateus, Treyer, A., A.
Published: Journal of Cellular Physiology, 2021:236:5885–5894
2024 | Journal Articles
Pretreatment with IL-15 and IL-18 rescues natural killer cells from granzyme B-mediated apoptosis after cryopreservation
Authors: Plachta, Berjis, Sheppard, Johnson, N., A., N.C., O., Finck, Scholler, Muthumani, A.V., J., D., Engel, Lanier, Aguilar, N.W., L.L., O.A., Chen, June, Pomp, L., C.H., O.
Published: Nature Communications; 2024:15:3937
2016 | Articles
Current approaches and future perspectives on strategies for the development of personalized tissue engineering therapies.
Authors: Neves LS, Rodrigues MT, Reis RL, Gomes ME
Published: Expert Review of Precision Medicine and Drug Development. Vol 1, Iss. 1, 2016
September 2024 | Journal Articles
Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control, single-blind, multiple-center clinical trial
Authors: Chen, Chang, C.F., C-S., Hung, Hu, Y-P., C.C., Tsai, Wu, C-C., C.T., Chang, Wu, Y., H-T H.
Published: Stem Cell Research & Therapy, 2021;12, 562
September 2024 | Journal Articles
Engineered CD47 protects T cells for enhanced antitumour immunity.
Authors: Labanieh, Fernandez-Pol, Martinez-Velez, Mount, Yamada-Hunter, Majzner, Desai, Banuelos, Lin1, Cochran, J.R., L., S., N., C.W., S.A., R.G., M.H., A., F., Radosevich, Mackall, Bjelajac, Kuo, Xu1, Chen, Theruvath, Weissman, Good, Khan, M.T., C.L., J., C.J., P., Y., J., I.L., Z., O., Wasserman, Leruste, Murty, Sorensen, Huang, Heitzeneder, McIntosh, Sahaf1, Polak, S.L., A., T., P.H., J., S., B.J., B., R., Spiegel, Dhingra, Ehlinger, Monje, Delaidelli, Marjon, Freitas, Sotillo, May, A., J.Y., S., Z., M., A., K.D., K.A., E.
Published: Nature 630, 457–465 (2024).
October 2023 | Articles
Surgical meshes coated with mesenchymal stem cells provide an anti-inflammatory environment by a M2 macrophage polarization.
Authors: Blázquez R, Sánchez-Margallo FM, Alvarez V, Uson A, Casado JG
Published: Acta Biomaterialia
2022 | Journal Articles
Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation
Authors: Mukherjee, Bibby, Merle, S., J.A., N.S., West, Afzali, Agarwal, E.E., B., D., Larochelle, Kemper, Freiwald, A., C., T., Chinian, Zhang, Kunz, F., N.R., N.
2012 | Posters
Developing Patient-specific Cell Therapy Manufacturing Processes
Authors: Keefe R, Carpenito C, Chin R, Rowley J, Schroeder J, Neo BH, McAfee E, Pattasseril J, Varadaraju H, Lock L
Published: Lonza Walkersville, Inc.
2024 | Articles
SeqVerify: An accessible analysis tool for cell line genomic integrity, contamination, and gene editing outcomes
Authors: Pierson Smela, M., Pepe, V., Lubbe, S., Kiskinis, E., Church, G.M.
Published: Stem Cell Reports
2024 | Protocol
Protocol for the generation, characterization, and functional assays of organoid cultures from normal and cancer-prone human esophageal tissues
Authors: Zhang, S., Cheng, G., Zhu, S., Lin, D., Wu, C.
Published: STAR Protocols
2024 | Articles
Assessing a single-cell multi-omic analytic platform to characterize ex vivo-engineered T-cell therapy products.
Authors: Moshref, M., Lo, JH-H., McKay, A., Camperi, J., Schroer, J., Ueno, N., Wang, S., Gulati, S., Tarighat, S., Durinck, S., Lee, H.Y., Chen, D
Published: Frontiers in Bioengineering and Biotechnology
2024 | Articles
Comparative study of systemic and local delivery of mesenchymal stromal cells for the treatment of chronic kidney disease.
Authors: Gregersen, E., Kresse, J-C, Atay, J.C.L., Boysen, A.T., Nejsum, P., Eijken, M. Nørregaard, R.
Published: Frontiers in Cell and Developmental Biology
2024 | Articles
An integrated single-cell reference atlas of the human endometrium.
Authors: Marečková, M., Garcia-Alonso, L., Moullet, M., Lorenzi, V., Petryszak, R., Sancho-Serra, C., Oszlanczi, A., Mazzeo, C.I., Wong, F.C.K., Kelava, I., Hoffman, S., Krassowski, M., Garbutt, K., Gaitskell, K., Yancheva, S., Woon, E.V., Male, V., Granne, I., He
Published: Nature Genetics
2024 | Articles
PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function
Authors: He, H., Bell, S.M., Davis, A.K., Zhao , S., Sridharan, A., Na, C-L, Guo, M., Xu, Y., Snowball, J., Swarr, D.T., Zacharias, W.J., Whitsett, J.A.
Published: Nature Communications
2016 | Articles
Intrapericardial Delivery of Cardiosphere-Derived Cells: An Immunological Study in a Clinically Relevant Large Animal Model
Authors: Blázquez R, Sánchez-Margallo FM, Crisóstomo V, et al.
Published: PLoS ONE
September 2024 | Journal Articles
Impact of Manufacturing Procedures on CAR T Cell Functionality
Authors: Watanabe, N, Mo, F. and McKenna, MK
Published: Frontiers in Immunology, 2022,13:876339
September 2024 | Journal Articles
The best protocol to treat equine skin wounds by second intention healing: A scoping review of the literature
Authors: Ribeiro, G., Carvalho, L., Borges, J., Prazeres, J.
Published: Animals, 2024;14:10:1500
2016 | Articles
Successful expansion of functional and stable regulatory T Cells for immunotherapy in liver transplantation
Authors: Safinia N, Vaikunthanathan T, Fraser H, Thirkell S, et al.
Published: Onotarget
September 2024 | Protocol
Creating iPSC lines with Ribonucleoprotein (RNP): Nucleofection, Single-cell Sorting, Genotyping, and Line Maintenance Protocol
Authors: Gill, K., Sachdev, A., Conklin, B., Clelland, C.
Published: protocols.io, 2022, PROTOCOL integer ID: 62319
September 2024 | Journal Articles
Comparison of hematopoetic recovery in multiple myeloma patients undergoing autologous transplantation using hematopoetic progenitor cells cryopreserved in laboratory-made freeze media or commercially available CryoStor CS10®
Authors: Christian, York, R., J., Vohra, Huang, F., J., Posey, Bradford, A., A., Lin, Horne, D., R.
Published: Cytotherapy, 2024:26:6, Supplement: S92-S93
2016 | Articles
The iXCELL-DCM Trial: Rationale and Design.
Authors: Henry TD, Schaer GL, DeMaria A, Recker D, Remmers AE, Goodrich J, Patel A.
Published: Cell Transplantation
September 2024 | Journal Articles
Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Invididuals With Anti-Nuclear Antibodies
Authors: Bookman, Gupta, Nassar, A., R., C., Johnson S. R., Wither, Vanlieshout E., Hiraki L.T., J.E., Mainion K., Ahmad, Bonilla D., Z., Kim M., Touma, Muñoz-Grajales, Z., C.
Published: Frontiers in Immunology. 2022; 13:886442
September 2024 | Journal Articles
Selective haematological cancer eradication with preserved haematopoiesis
Authors: Durzynska, Zuin, Kunz, Garaudé, Manquen, Tsai, Beerlage, I., J., C., S., G., S.Q., A., Seyres, Wellinger, Burgold, Tamburini, Marone, Li, Simonetta, D., L.C., T., J., R., Y., F., Urlinger, Dell' Aglio, Kirby, Wang, Bertoni, Lepore, Larrue, S., A., I., S., F., R., C., Jeker, Juskevicius, Van Berkel, Katta, Widmer, Devaux, Camus, A., L.T., D., P.H., V., C.C., A.
Published: Nature. 2024;630:8017:728-735.
2021 | Articles
Cryopreservation: An Overview of Principles and Cell-Specific Considerations
Authors: Whaley, Alexander, D., M., & Lakey, Damyar, J., K., Witek, R., Mendoza, A.
Published: Cell Transplantation
2022 | Journal Articles
Efficient Induction of Antigen-Specific CD8+ T-Cell Responses by Cationic Peptide-Based mRNA Nanoparticles
Authors: D’haese, Vanham, S., G., Aerts, Laeremans, J.L., T., den Roover, S., Allard, S.D.
Published: Pharmaceutics. 2022, 14, 1387
September 2024 | Journal Articles
The temporal progression of lung immune remodeling during breast cancer metastasis
Authors: McGinnis, Goga, C.S., A., Reticker-Flynn, Miao, N.E., Z., Winkler, Superville, J., D., Satpathy, Yao, A.T., W.
Published: Cancer Cell, 2024;42:6:1018-1031.e6
2016 | Articles
The Cocoon® Platform Combined With the 4D-Nucleofector® LV Unit: A Non-viral Workflow for Modifying Primary T Cells
Authors: Schroeder, Hwa Neo, Daita, J., B., K., Sei, Abraham, Bandapalle, J., E., S., Zander, Shi, O’Connor, M., Y., J., Gleissner, Lin, T., K.
Published: Lonza
2022 | Journal Articles
Novel topical allogeneic bone-marrow-derived mesenchymal stem cell treatment of hard-to-heal diabetic foot ulcers: a proof of concept study
Authors: Andersen, Steeneveld, J.A., E., Kirketerp‑Møller, Rasmussen, K., A., O’Brien, Frimodt‑Møller, T., M., and Rossing, Engberg, P., S.
Published: Stem Cell Research & Therapy. 2022, 13:280
September 2024 | Journal Articles
Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes
Authors: Sanchez, Kramme, Estevez, Slifkin, Paulsen, Kelk, McCulloh, Kats, M., C.C., S.L., R.E., B., D.A., D.H., S., Potts, Belchin, Noblett, Smela, Piechota, Forti, Copperman, K.S., P., A.D., M.P., S., M., A.B., Ordonez-Perez, Rockwell, Lee, Figueroa, Fortuna, Barrachina, Marcinyshyn, D., G., J.A., A.B., P.R.J., F., S., Klein, Marchante, Buyuk, Aschenberger, Chatterjee, Giovannini, Wiemer, K., J.U., M., E., C., P., A.
Published: Journal of Assisted Reproduction and Genetics. 2024;May 30
2016 | Articles
Effective Hypothermic Storage of Human Pluripotent Stem Cell-Derived Cardiomyocytes Compatible With Global Distribution of Cells for Clinical Applications and Toxicology Testing
Authors: Correia C, Koshkin A, Carido M, Espinha N, Saric T, Lima P, Serra M, Alves P
Published: Stem Cells Translational Medicine
September 2024 | Journal Articles
Fate Bias and Transcriptional Memory of human B cells
Authors: Swift, M., Horns, F., and Quake, S.R.
2024 | Journal Articles
A high-density microfluidic bioreactor for the automated manufacturing of CAR T cells
Authors: Ram, Luah, Sin, Lee, Fong, R, Y.H., W.X., Y.H., S.Y., Tan, J, Wu, Jagannathan, Seng, J.H.L., Tucker-Kellogg, X., N.S., M.S., Sandikin, L., Raymond, Teo, Soh, D., Birnbaum, J.J., D.B.L., S.Y., Cheung, M.E., Lim, Kairi, Chen, Q., K.W., F.L.W.I., F.
Published: Nature Biomeical Engineering, 2024;Jun 4
October 2023 | Articles
Transplantation of Defined Populations of Differentiated Humas Neural Stem Cell Progeny
Authors: Fortin JM, Reynolds BA, Azari H, Zheng T, Darioosh RP, Schmoll, ME, Vedam-Mai V, Deleyrolle LP
Published: Scentific Reports