Cryopreservation

Articles

2024 | Cryopreservation | Articles

Assessing a single-cell multi-omic analytic platform to characterize ex vivo-engineered T-cell therapy products.

Authors: Moshref, M., Lo, JH-H., McKay, A., Camperi, J., Schroer, J., Ueno, N., Wang, S., Gulati, S., Tarighat, S., Durinck, S., Lee, H.Y., Chen, D

Published: Frontiers in Bioengineering and Biotechnology

2024 | Cryopreservation | Articles

Comparative study of systemic and local delivery of mesenchymal stromal cells for the treatment of chronic kidney disease.

Authors: Gregersen, E., Kresse, J-C, Atay, J.C.L., Boysen, A.T., Nejsum, P., Eijken, M. Nørregaard, R.

Published: Frontiers in Cell and Developmental Biology

2024 | Cryopreservation | Articles

Cryopreserving CAR-T cells in a novel rigid container maintains their phenotype and function compared to conventional cryobags and cryovials

Authors: Pleitez D, Park M, Safford M et al.

Published: Cell & Gene Therapy Insights

2024 | Cryopreservation | Articles

SeqVerify: An accessible analysis tool for cell line genomic integrity, contamination, and gene editing outcomes

Authors: Pierson Smela, M., Pepe, V., Lubbe, S., Kiskinis, E., Church, G.M.

Published: Stem Cell Reports

2022 | Cryopreservation | Articles

Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Invididuals With Anti-Nuclear Antibodies

Authors: C., Z., Gupta, Nassar, Bookman, R., C., A., Vanlieshout E., Johnson S. R., Wither, Mainion K., Hiraki L.T., J.E., Bonilla D., Ahmad, Kim M., Z., Muñoz-Grajales, Touma

Published: Frontiers in Immunology

2022 | Cryopreservation | Articles

Creating iPSC lines with Ribonucleoprotein (RNP): Nucleofection, Single-cell Sorting, Genotyping, and Line Maintenance Protocol

Authors: C., Gill, K., Sachdev, A., Conklin, B., Clelland

Published: protocols.io, 2022, PROTOCOL integer ID: 62319

2022 | Cryopreservation | Articles

Efficient Induction of Antigen-Specific CD8+ T-Cell Responses by Cationic Peptide-Based mRNA Nanoparticles

Authors: S.D., D’haese, Vanham, S., G., Laeremans, Aerts, T., J.L., den Roover, S., Allard

Published: Pharmaceutics

2022 | Cryopreservation | Articles

Impact of Manufacturing Procedures on CAR T Cell Functionality

Authors: Watanabe, N, Mo, F. and McKenna, MK

Published: Frontiers in Immunology

2021 | Cryopreservation | Articles

Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control, single-blind, multiple-center clinical trial

Authors: H-T H., Y., Chen, Chang, CF., C-S., Hu, Hung, CC., Y-P., Wu, Tsai, CT., C-C., Wu, Chang

Published: Stem Cell Research & Therapy

2019 | Cryopreservation | Articles

A human liver cell atlas reveals heterogeneity and epithelial progenitors.

Authors: Durand, Grün, Aizarani, S., D., N., Herman, Saviano, J. S., A., Pessaux, Sagar, P., Mailly, Baumert, L., T. F.

Published: Nature

2019 | Cryopreservation | Articles

Automated Clinical Grade Expansion of Regulatory T Cells in a Fully Closed System

Authors: A., D., A., Marín Morales, Oelschlägel, Keßler, J. M., U., J., Münch, Hölig, Bonifacio, N., K., E., Peter, Böhm, Bornhäuser, M., K., T., Fuchs, Freund, Flach

Published: Frontiers In Immunology

2019 | Cryopreservation | Articles

CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions

Authors: K., A., S. S., Jung, Poot, Zwart, Hammerl, J., R. A., E., F., Buisman, Bystrykh, Schepers, Skokova, S. C., L. V., H., Y., Weersing, de Haan, Dekker, Kooistra, S. M., E., G., M. R., Klauke, Dethmers-Ausema, Lazare

Published: Cell Reports

2019 | Cryopreservation | Articles

Checkpoint kinase 1 is essential for fetal and adult hematopoiesis

Authors: G., Schuler, Erlacher, F., M., Afreen, Villunger, S., A., Manzl, C., Häcker

Published: EMBO Reports

2019 | Cryopreservation | Articles

Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs

Authors: Maminishkis, M. M., B. S., M., J., L., A., Sharma, Miyagishima, Dejene, Stanzel, Stankewicz, Charles, Amaral, R., K. J., R., B., C., S., J. and Bharti, Khristov, McGaughey, Hotaling, Qian, Wan, McGill, K., V., D., N., H., Q., T., Rising, Villasmil, Li, Wong, Zhang, Miller, C., A., R., Y., W., S., Campos, Jha, Mattapallil, Stoddard, Chase

Published: Science Translational Medicine

2019 | Cryopreservation | Articles

Closed and semi-automated processing of CAR T cells

Published: GE Healthcare Life Sciences

2019 | Cryopreservation | Articles

Colonic epithelial cell diversity in health and inflammatory bowel disease.

Authors: E., M., R. S., J., R., Parikh, Hublitz, Aulicino, Björklund, Chen, Koohy, K., P., A., E., H. H., H., Antanaviciute, Bao, Lagerholm, Kessler, Alham, Simmons, A., L., C., B. M., N. K., A., Fawkner-Corbett, Lukomska, Davis, Fischer, Ashley, N., D., J., S., R., Johnson, Jagielowicz, Andev, Kinchen, Goldin

Published: Nature

2019 | Cryopreservation | Articles

Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives

Authors: A., Cao, Mummery, X., C. L., Yakala, Orlova, G. K., V. V., van den Hil, F. E., Cochrane

Published: Stem Cell Reports

2019 | Cryopreservation | Articles

Enhancing Lentiviral and Alpharetroviral Transduction of Human Hematopoietic Stem Cells for Clinical Application

Authors: K. F., A., Schott, Santilli, Thrasher, J. W., G., A. J., León-Rico, Armant, D., M. A., Ferreira, Schambach, C. B., A., Buckland, Cavazza

Published: Molecular Therapy - Methods & Clinical Development

2019 | Cryopreservation | Articles

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells

Authors: J. H., Mitsunaga, Shioda, S., T., Shioda, K., Isselbacher, K. J., Hanna

Published: Journal of Visualized Experiments Journal

2019 | Cryopreservation | Articles

HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness

Authors: E. F., F., S., U. K., Kuo, Brenner, Wei, Rätsch, Shanaj, D., M. B., K., G., S., Ding, Bykerk, Rao, Ivashkiv, Oliver, J., V. P., D. A., L. B., D. J., Cohn, Goodman, Rozo, Donlin, Echeverria, A. P., I. S., S. M., C., L. T., DiCarlo, Zhang, Raychaudhuri, Sokhi

Published: Science Translational Medicine

2019 | Cryopreservation | Articles

How do I structure logistic processes in preparation for outsourcing of cellular therapy manufacturing?

Authors: A., Chen, West, L. N., K., Collins‐Johnson, Stroncek, N., D. F., Sapp, Panch, N., S. R., Pickett

Published: Transfusion

2019 | Cryopreservation | Articles

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies

Authors: J., Xia, Rossi, X., J. J., Li, H., Satheesan, S., Zhou

Published: Journal Of Visualized Experiments

2019 | Cryopreservation | Articles

Huntington’s Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support.

Authors: N. D., Garcia, Kemp, V. J., P. J., Rushton, Svendsen, D. J., C. N., Tom, Mattis, C. M., V. B., Allen

Published: Frontiers In Neuroscience

2019 | Cryopreservation | Articles

Improved expansion of equine cord blood derived mesenchymal stromal cells by using microcarriers in stirred suspension bioreactors.

Authors: A. H., Roberts, Walsh, E. L., T., Dang, Koch, T., T. G., Lepage, Kallos, S. I. M., M. S., Alizadeh

Published: Journal Of Biological Engineering

2019 | Cryopreservation | Articles

In Vitro And In Vivo Evaluation Of Possible Pro-Survival Activities Of PGE2, EGF, TPO And FLT3L On Human Hematopoiesis

Authors: M., Demmerath, E., Bohler, S., Kunze, M., Erlacher

Published: Haematologica

2019 | Cryopreservation | Articles

In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials

Authors: G. F., F., C., A., Tappenbeck, Orgill, Dehio, Kluth, Esterlechner, N., D. P., U., M. A., J., Schröder, Beck, Dieter, Frank, H. M., J., K., N. Y., Niebergall-Roth, Frank, Kraft, Scharffetter-Kochanek, K., E., M. H., K., Murphy, Hassinger, Ganss, Kerstan

Published: Cytotherapy. 2019; 21(5), 546-560

2019 | Cryopreservation | Articles

Intratumoral genetic and functional heterogeneity in pediatric glioblastoma

Authors: Lafay-Cousin, Simons, M., M. J., Y., J. C., M. D., L., B. D., Hoffman, Coutinho, Nikolic, Mungall, Ellestad, Pugh, Resnick, Chan, M., F. J., A., A. J., K., T. J., A. C., J. A., Gillmor, Zhu, Narta, Moore, Dang, Dirks, Scherer, Morrissy, A., Y., K., R. A., N. H., P. B., S. W., A. S., Kunz, Luu, Zarrei, Marra, Cavalli, Strother, Senger, Gallo, F. M. G., D. J., B., M., M. A., M., D., D. L., Kushida, Johnston, Ma, King, Taylor

Published: Cancer Research. March 15 2019

2019 | Cryopreservation | Articles

Large-scale expansion and characterization of CD3+ T-cells in the Quantum® Cell Expansion System

Authors: B., Coeshott, C., Vang, B., Jones, M., Nankervis

Published: Journal Of Translational Medicine

2019 | Cryopreservation | Articles

Managing starting material stability to maximize manufacturing flexibility and downstream efficiency

Authors: Clarke, D., Smith, D.

Published: Cell & Gene Therapy Insights

2019 | Cryopreservation | Articles

Manufacturing and preclinical validation of CAR T cells targeting ICAM-1 for advanced thyroid cancer therapy

Authors: N. J., I. M., J., Vedvyas, Hofe, Fahey, Besien, Y., E. V., T. J., K. V., McCloskey, Jin, Zarnegar, Gaudet, J. E., M. M., R., I., Yang, Hsu, Law, P., Y., Y. S., Kim, Min, Hsu

Published: Scientific Reports

2019 | Cryopreservation | Articles

Manufacturing chimeric antigen receptor T cells: issues and challenges

Authors: K., Roddie, Lowdell, C., M., O'Reilly, M., Dias Alves Pinto, J., Vispute

Published: Cytotherapy

2019 | Cryopreservation | Articles

On-demand serum-free media formulations for human hematopoietic cell expansion using a high dimensional search algorithm

Authors: Kim, M., Audet, J.

Published: Communications Biology

2019 | Cryopreservation | Articles

ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells. 

Authors: W., B., H., C., J., Zhong, Lai, Cao, Xu, Li, Yan, W., C., X., G., R., D., Xu, Wang, Li, Olkkonen, Luo, M., T., D., V. M., C., Li, Du, Chen, Lei, Pan, G., C., X., H., P., Zhang, Zhu, Chen, Hu, Xu

Published: Cell Reports

2019 | Cryopreservation | Articles

Preservation of cell-based immunotherapies for clinical trials

Authors: D. H. and Hubel, Li, A., R., Johnson, R., Yu, G., McKenna

Published: Cytotherapy. 2019; 21(9), 943-957

2019 | Cryopreservation | Articles

Qualification of cellular starting materials for cell-based therapies

Authors: Read, E.

Published: Cell & Gene Therapy Insights

2019 | Cryopreservation | Articles

Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)

Authors: K., S. A. J., M., Paitazoglou, Kastrup, van Klarenbosch, Ekblond, C., J., B., A., Bergmann, Wojakowski, Haack-Sørensen, M. W., W., M., Vrtovec, Michalewska-Wudarczyk, Jaquet, K., B., A., Vrangbæk, Chamuleau, Gyöngyösi

Published: European Journal of Heart Failure

2019 | Cryopreservation | Articles

Reduced T-cell Numbers and Elevated Levels of Immunomodulatory Cytokines in Metastatic Prostate Cancer Patients De Novo Resistant to Abiraterone and/or Enzalutamide Therapy

Authors: S. W., J., Pal, Duttagupta, Kortylewski, S. K., P., M., Moreira, Lucia, D., M., Won, Jones, H., J., White, Hsu

Published: International Journal Of Molecular Sciences

2019 | Cryopreservation | Articles

Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform

Authors: H. D., C., V. P., T. JR, R., Stacey, Parmar, Chandra, Stacey, Halliwell, G. N., M., A., A. R., J. A., Andrews, Panico, Cossu, Tedesco, Hewitt, P. W., M. B., G., F. S., Z., Barbaric, Pisupati, Csontos, Thompson, McCall, M., I., V., L., O., Moore, Boiers, Shichkin, Frith, Wagey

Published: Regenerative Medicine

2019 | Cryopreservation | Articles

The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells

Authors: T., S., J., A., M. W., Adane, Kelly, Minhajuddin, Kume, Reisz, Jordan, B., K. K., M., T., J. A., C. T., Ye, Myers, Stevens, Campbell, Zaberezhnyy, H., J. R., B. M., E. L., V., Khan, Ashton, Jones, Pollyea, Gasparetto, M., N., J. M., C. L., D. A., Ho, Pei, Siegenthaler, D’Alessandro, Becker

Published: Cell Reports

2019 | Cryopreservation | Articles

The Role of Mesenchymal Stromal Cells in the Management of Osteoarthritis of the Knee [Online First]

Authors: Thej, C., Gupta, P.

Published: Update on Mesenchymal and Induced Pluripotent Stem Cells

2018 | Cryopreservation | Articles

A comprehensive method for identification of suitable reference genes in extracellular vesicles

Authors: de Couto, Gouin, Walravens, Peck, Rodriguez-Borlado, Antes, Smith, Johnson, Marban, Li, Ibrahim, Vaturi, Middleton

Published: JOURNAL OF EXTRACELLULAR VESICLES

2018 | Cryopreservation | Articles

A Humanized Mouse Model Generated Using Surplus Neonatal Tissue

Authors: Kamp T., Brown M., Thomson J., Zhou Y., Anagnostopoulos P., McIntosh B., Burlingham W., Norman I., Lou H., Biermann M., Sullivan J.

Published: Stem Cell Reports

2018 | Cryopreservation | Articles

A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials

Authors: Hope A., Lombardi G., Fraser H., Fisher C., Safinia N., Hilton R., Grageda N., Game D., Thirkell S., Harden P., Lowe K., Bushell A., Fry LJ., Wood K., Scottá C., Lechler R.

Published: Molecular Therapy: Methods & Clinical Development

2018 | Cryopreservation | Articles

A Subretinal Cell Delivery Method via Suprachoroidal Access in Minipigs: Safety and Surgical Outcomes.

Authors: M., de Smet, & Khan, M., I., Lynch, J., Dejneka, N., Keane

Published: Investigative Opthalmology & Visual Science

2018 | Cryopreservation | Articles

Anti-fibrotic Effects of CXCR4-Targeting i-body AD-114 in Preclinical Models of Pulmonary Fibrosis

Authors: Griffiths, K., Habiel, D.M., Jaffar, J. et al.

Published: Scientific Reports

2018 | Cryopreservation | Articles

Anti-Inflammatory Therapeutic Development and Optimization of Umbilical Cord Tissue Derived Mesenchymal Stem Cells

Authors: M., Sutton, Folz, M., M., Kaur, Caplan, S., A., Brown, and Bonfield, K., T., Skiles

Published: Journal Of Stem Cell Research & Therapy

2018 | Cryopreservation | Articles

Application of Raman Spectroscopy and Univariate Modelling As a Process Analytical Technology for Cell Therapy Bioprocessing

Authors: Baradez MO, Biziato D, Hassan E, Marshall D.

Published: Frontiers In Medicine

2018 | Cryopreservation | Articles

Autologous Mesenchymal Stromal Cells Prevent Transfusion-elicited Sensitization and Upregulate Transitional and Regulatory B Cells

Authors: S. E., A., Zhang, Redfield, Z., R. R., Wilson, Reese, N. A., S. R., Chinnadurai, Galipeau, R., J., Panzer, Djamali

Published: Transplantation Direct

2018 | Cryopreservation | Articles

Beneficial Effects of Human Mesenchymal Stromal Cells on Porcine Hepatocyte Viability and Albumin Secretion

Authors: C. and Buhler, F., J., Montanari, L. H., Passemard, Thomas, E., S., A., Pimenta, Meier, Schuurman, J., R. P. H., H., Szabó, Meyer, Gerber-Lemaire, S., L., J., Gonelle-Gispert, Noverraz, Sidibe

Published: Journal of Immunology Research

2018 | Cryopreservation | Articles

Biomanufacturing for clinically advanced cell therapies. .

Authors: R. N., D., B., S., Aijaz, Anderson, LeBlon, Tischfield, A., D. G., C., J., Li, Ritz, Fenton, Maus, M., J., O. S., M. V., Smith, Preti, Olabisi, Deans, R., D., R., R. M., Barcia, Khong, Parekkadan, Libutti

Published: Nature Biomedical Engineering

2018 | Cryopreservation | Articles

CD73, CD90, CD105 and Cadherin-11 RT-PCR Screening for Mesenchymal Stem Cells from Cryopreserved Human Cord Tissue.

Authors: C., Pham, Chen, H., M., Tonai, R., Wu, M., Birtolo

Published: Int. J. Stem Cells 2018; 11(1): 26-38

2018 | Cryopreservation | Articles

Clinical Cellular Therapeutics Accelerate Clot Formation.

Authors: Y., George, Gill, M. J., B. S., Prabhakara, Wade, K., C. E., Toledano-Furman, Olson, N. E., S. D. and Cox, Wang, C. S.

Published: STEM CELLS Translational Medicine

2018 | Cryopreservation | Articles

Collagenase Impacts the Quantity and Quality of Native Mesenchymal Stem/Stromal Cells Derived during Processing of Umbilical Cord Tissue

Authors: Taghizadeh R., Cetrulo K., Cetrulo C.

Published: Cell Transplantation

2018 | Cryopreservation | Articles

Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients

Authors: Maghami E., Sampath S., Kortylewski M., Won H., Massarelli E., Li M., Frankel P., Vora N., Vora L.

Published: Oncotarget

2018 | Cryopreservation | Articles

Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth

Authors: Seaman, J., H. J., P., T. G., P. D., M. S., Wagh, Chuang, Learn, Williams, Smith, Haynes, Hahn, K., G., G. H., I., A. G., B. F., B. H. and Korber, Kreider, Rawi, Giorgi, Overbaugh, Gondim, Shaw, B., E. F., R., E., J., M. V., G. M., Li, Cai, Hraber, Gao, Gillis, Borrow, L., Y., F., P. T., F., P., Wandzilak, Barbian, Pellegrino, Decker, Kwong

Published: Cell Reports

2018 | Cryopreservation | Articles

Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA–Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy

Authors: Y., P., Hung, Jin, Shivakumar, C., Q., R., Xu, Viley, Peshwa, X., A., M. V. and Emens, Li, Allen, L. A., L., C., Ma, Natarajan

Published: Human Gene Therapy

2018 | Cryopreservation | Articles

Development of in vitro enteroids derived from bovine small intestinal crypts.

Authors: A., J., Hamilton, Paxton, Innes, C. A., E., E., Young, Thomson, Morrison, R., S., L. J. and Mabbott, Jayaraman, Katzer, N. A., S., F., Sehgal, Hope

Published: Veterinary Research

2018 | Cryopreservation | Articles

Discogenic cell transplantation directly from a cryopreserved state in an induced intervertebral disc degeneration canine model

Authors: T., M., Hiraishi, Erickson, S., I., Schol, Silverman, J., L., Sakai, Foley, D., K., Nukaga, Watanabe

Published: Journal of Orthopaedic Research Spine

2018 | Cryopreservation | Articles

Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment

Authors: C. B., K. S., M., H. H., Wagner, Newman, MacFarlane, El-Deiry, Ross, J., J. H., A. W., W. S., E. A., Kline, Kaufman, Olszanski, Ralff, C. L., H., A. J., M. D., Zhou, Bertino, Cai, Zloza, A., L., J., K. Q., Chesson, Campbell, Stein, Hensley

Published: The Journal of Clinical Investigation

2018 | Cryopreservation | Articles

Effective Targeting of TAG72+ Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells

Authors: M., J., Murad, Chang, Cristea, J. P., W., M., Kozlowska, Yazaki, Forman, A. K., P., S. J. and Priceman, Lee, Colcher, S. J., H. J., D., Ramamurthy, Shively

Published: Frontiers in Immunology

2018 | Cryopreservation | Articles

Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs

Authors: Navarengom K., Dunbar C., Lin Y., Schwartzbeck R., Boehm M., Liu H., San H., Zou J., Klein M., Yu Z., Ostrominski J., Liu C., Hong S., Linask K., Yada R., Beers J., Chen G., Qiu L.

Published: Scientific Reports

2018 | Cryopreservation | Articles

Engineering Scalable Manufacturing of High-Quality Stem Cell-Derived Cardiomyocytes for Cardiac Tissue Repair

Authors: Dunn, K., and Palecek, S.

Published: Frontiers In Medicine

2018 | Cryopreservation | Articles

Establishing and Maintaining an Extensive Library of Patient-Derived Xenograft Models

Authors: B., Mattar, Guzman, M., S., McCarthy, de Stanchina, C. R., E., Kulick, A. R., Qeriqi

Published: Frontiers in Oncology

2018 | Cryopreservation | Articles

Exosomes From Human Cardiac Progenitor Cells for Therapeutic Applications: Development of a GMP-Grade Manufacturing Method

Authors: A., V., Andriolo, Soncin, Vassalli, G., S., G., Provasi, Torre, Turchetto, E., T., L., Lo Cicero, Milano, Barile, L. and Radrizzani, V., G., M., Brambilla, Biemmi

Published: Frontiers in Physiology

2018 | Cryopreservation | Articles

Human Umbilical Cord Mesenchymal Stem Cells Preserve Adult Newborn Neurons and Reduce Neurological Injury after Cerebral Ischemia by Reducing the Number of Hypertrophic Microglia/Macrophages

Authors: Chang CP, Lin W, Lin HJ., Hsuan YC, Lin MT, Kuo TW, Lin CH, Su YC, Niu KC

Published: Cell Transplantation

2018 | Cryopreservation | Articles

Increased sensitivity of Treg cells from patients with PBC to low dose IL-12 drives their differentiation into IFN-γ secreting cells.

Authors: D., D. E., Liaskou, Akiror, Bowman, E., S., S. J., Patel, Krishna, Barone, S. R., M., F., Webb, Mells, Fisher, B. A. and Hirschfield, G., G., G. M., Bagkou Dimakou, Jones

Published: Journal Of Autoimmunity (2018).

2018 | Cryopreservation | Articles

Industrializing Autologous Adoptive Immunotherapies: Manufacturing Advances and Challenges

Authors: A., Iyer, R. K., Bowles, P. A., Kim, H., Dulgar-Tulloch

Published: Frontiers In Medicine

2018 | Cryopreservation | Articles

Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells

Authors: D. C., Halaidych, Riminucci, O. V., M., Freund, Mummery, C., C. L. and Orlova, van den Hil, V. V., F., Salvatori

Published: Stem Cell Reports

2018 | Cryopreservation | Articles

Methods for high-dimensional analysi+s of cells dissociated from cryopreserved synovial tissue

Authors: Ivashkiv LB, Mizoguchi F, Pitzalis C, Eisenhaure TM, Boyle DL, Donlin LT, Goodman SM, Gutierrez-Arcelus M, Gregersen PK, Li S, Brenner MB, Rao DA, Robinson WH, Lieb DJ, Firestein GS, Browne EP, Anolik JH., Wei K, Utz PJ, Keegan J, Raychaudhuri S, Chicoine A, Slowikowski K, Lederer JA, Muskat K, Moreland LW, Sutherby D, McGeachy MJ, Gravallese EM, Hillman J, Holers VM, Noma A; Accelerating Medicines Partnership RA/SLE Network; Nusbaum C, Kelly S, Turner JD, Boyce BF, Rozo C, Bykerk VP, Pernis AB, Meednu N, Hacohen N, Ricker E, Filer A

Published: Arthiritis Research & Therapy

2018 | Cryopreservation | Articles

Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis

Authors: J. S., I., E. W., L. T., Fonseka, Helfgott, Hannes, Ermann, Lederer, C. Y., S. M., S. K., J., J. A., Rao, Todd, Slowikowski, Lee, Weinblatt, D. A., D. J., K., Y. C., M. E., Teslovich, Bykerk, Gurish, Brenner, Massarotti, E. M., N. C., V. P., M. F., M. B. and Raychaudhuri, Coblyn, Korsunsky, Karlson, Donlin, S.

Published: Science Translational Medicine

2018 | Cryopreservation | Articles

Modeling Idiopathic Pulmonary Fibrosis in Humanized SCID Mice

Authors: C., Habiel, D., Espindola, M., Coelho, A., & Hogaboam

Published: The American Journal of Pathology

2018 | Cryopreservation | Articles

Neuroprotective Action of Human Wharton’s Jelly-Derived Mesenchymal Stromal Cell Transplants in a Rodent Model of Stroke

Authors: Li-Wei Kuo, Kuo-Jen Wu, Yun Wang, Seong-Jin Yu, Chia-Wen Chiang, Yu-Wei Lee, B Linju Yen, Pei-Chi Tseng, Chun-Sen Hsu

Published: Cell Transplantation

2018 | Cryopreservation | Articles

Off the shelf T cell therapies for hematologic malignancies

Authors: McCreedy, B. J., Senyukov, V. V., Nguyen, K. T.

Published: Best Practice & Research Clinical Haematology

2018 | Cryopreservation | Articles

Patient-derived xenograft cryopreservation and reanimation outcomes are dependent on cryoprotectant type

Authors: Thomas, Ivanics, Fleming, Bergquist, Truty, Liu, Kim, Kang, Katz, Rios Perez

Published: Laboratory Investigation

2018 | Cryopreservation | Articles

Practical considerations for clinical use of mesenchymal stem cells: From the laboratory to the horse.

Authors: C., Barrachina, & Vázquez, L., F., Romero, A., Zaragoza, P., Rodellar

Published: The Veterinary Journal

2018 | Cryopreservation | Articles

Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells.

Authors: S. J., Higgins, Smith, J. R., P., T., S. E., G., M. K., R., Jin, Hjerrild, Soegaard, Baleanu, Marshall, Moyle, Detmers, de Jongh, J., K. A., M., I. N., J. M., S., F. J., W. A., Tarrant, Poulsen, Pattinson, Parracho, Dabbs, Payne, Lawrie, Berrie, R. D., L., D. J., H. M., R. A., R. O., A. M., E., Bolam, Jørgensen, Dulal, Tahiri-Alaoui, Nugent, Minassian, Douglas, Ashfield, F. L., E. J., T., P., A., R. and Draper, A. M., A. D., Barrett, Angell-Manning, Brenner, Silk, Whale

Published: NPJ Vaccines

2018 | Cryopreservation | Articles

Quantitative analysis of composite umbilical cord tissue health using a standardized explant approach and an assay of metabolic activity

Authors: K., Skiles, & Brown, M., H., Brown, K., Tatz, W., Swingle

Published: Cytotherapy

2018 | Cryopreservation | Articles

Regulatory T Cell Modulation of Immune Suppression

Published: Charles River

2018 | Cryopreservation | Articles

Scale-up of a perfusion-based dendritic cell generation process

Authors: J. M., Kozbial, A., Weinstein, H., Murthy, S. K., Rossi

Published: Cell Gene Therapy Insights

2018 | Cryopreservation | Articles

Substrate stiffness modulates the multipotency of human neural crest derived ectomesenchymal stem cells via CD44 mediated PDGFR signaling

Authors: Srinivasana A, Changa S-Y, Zhange S, Toh WS, Toh Y-C

Published: Biomaterials

2018 | Cryopreservation | Articles

Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses

Authors: A., Y., Rajamani, Vawter, Andres, U., M. P., A. M., Gross, Tang, Gottlieb, A. R., J., R. A., Hjelm, Gangalapudi, Sareen, D., B. E., V., Sequeira, Wang

Published: Cell Stem Cell

2018 | Cryopreservation | Articles

SV-BR-1-GM, A Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses An Immune Signature And Directly Activates CD4+ T Lymphocytes

Authors: J. P., S., T., Lacher, Wiseman, Fledderman, Perotti, M. D., C. L., E. L., N. H., Bauer, Williams, Petrie, Kong, G., W. V., T. D., Y. Y., Fury, Coleal-Bergum, Kwok, W. W., B., D. P., Wagner, Graeve, Hackett

Published: Frontiers In Immunology

2018 | Cryopreservation | Articles

Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons.

Authors: C., Fernandopulle, Gan, M., L., Prestil, Ward, R., M., Grunseich, C., Wang

Published: Current Protocols In Cell Biology

2018 | Cryopreservation | Articles

Tumor lysate particle loaded dendritic cell vaccine: preclinical testing of a novel personalized cancer vaccine

Authors: Berry, Hardin, Nichols, Vreeland, Yin, Clifton, Yu, Hale, Wagner, Herbert, Peoples, Greene, Jackson

Published: Immunotherapy

2017 | Cryopreservation | Articles

A Pilot Study Evaluating the Safety of Intravenously Administered Human Amnion Epithelial Cells for the Treatment of Hepatic Fibrosis

Authors: Lim R, Hodge A, Moore G, Wallace E, Slevert W

Published: Frontiers in Pharmacology

2017 | Cryopreservation | Articles

Antigen-specific immunoglobulin variable region sequencing measures humoral immune response to vaccination in the equine neonate

Authors: Tallmadge RL, Miller SC, Parry SA, Felippe MJB

Published: PLoS ONE

2017 | Cryopreservation | Articles

Applications and optimization of cryopreservation technologies to cellular therapeutics

Authors: De Mendonca J., Fuller B., Gonzalez-Molina J., Erro E., Poirier A., Selden C., Awan M, Chalmers S.

Published: Cell & Gene Therapy Insights - ISSN: 2059-7800

2017 | Cryopreservation | Articles

Best practices for cryopreserving, thawing, recovering, and assessing cells

Authors: Baust, Campbell, Harbell

Published: In Vitro Cellular and Developmental Biology —Animal

2017 | Cryopreservation | Articles

Biopreservation Best Practices for Regenerative Medicine GMP Manufacturing & Focus on Optimized Biopreservation Media 

Authors: Hawkins B, Abazari A, Mathew A

Published: Cell & Gene Therapy Insights - ISSN: 2059-7800 

2017 | Cryopreservation | Articles

Biopreservation Best Practices: A Cornerstone in the Supply Chain of Cell-based Therapies – MSC Model Case Study

Authors: Abazari A, Hawkins BJ, Clarke DM, Mathew AJ

Published: Cell Gene Therapy Insights

2017 | Cryopreservation | Articles

CD34− human placenta-derived mesenchymal stem cells protect against heat stroke mortality in rats

Authors: Lin, Lin, Hsuan, Su, Lin, Lin, Chen, Chang

Published:  Oncotarget

2017 | Cryopreservation | Articles

Clinical methods of cryopreservation for donor lymphocyte infusions vary in their ability to preserve functional T-cell subpopulations

Authors: Worsham D N, Reems J-A, Szczepiorkowski Z, McKenna D, et al.

Published: Transfusion

2017 | Cryopreservation | Articles

Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer

Authors: W., K. T., A. M., Y., Priceman, Wright, Murad, Brown, Yang, S. J., S., J. P., C. E. and Forman, X., Gerdts, Pal, Park, S. J., Urak, E. A., S., A. K., R., Tilakawardane, Reiter, Jeang, Weng, L., D., R. E., B., Chang, Kennewick, Wu, Yamaguchi

Published: Oncoimmunology

2017 | Cryopreservation | Articles

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo

Authors: Little LE., Wakeman D., Xie Z., Hiller BM., Perez-Rosello T., Marmion DJ., Guzman JN., McMahon CW., Surmeier J., Corbett GT., Kordower JH., Mangan KP., Ma J

Published: Stem Cell Reports

2017 | Cryopreservation | Articles

Cryopreserved Off-the-Shelf Allogeneic Adipose-Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure—A Safety Study

Authors: Qayyum, Kastrup, Mathiasen, Haack-Sorensen, Jorgenson, Juhl, Helqvist, Sondergaard, Elberg, Follin, Bruunsgaard, Lund, Ekblond, Johansen

Published: STEM CELLS TRANSLATIONAL MEDICINE

2017 | Cryopreservation | Articles

Development of a novel method for amniotic fluid stem cell storage

Authors: Zavatti M, Beretti F, Casciaro F, Comitini G, et al.

Published: Cytotherapy

2017 | Cryopreservation | Articles

Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis

Authors: Hamid, Fraser, Moore, Pass, Dwyer, Burgoyne, Turner, Atkinson, Forbes, Bailey, Campbell, Laurie, McGowan

Published: CytoTherapy

2017 | Cryopreservation | Articles

Ex Vivo-expanded Natural Killer Cells Derived From Longterm Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells

Authors: Hogg, Nham, Lee, Poznanski, Ashkar, Fan, Vahedi, Shenouda, Lee, Chew

Published: Journal of Immunotherapy: Post Author Corrections: November 17, 2017

2017 | Cryopreservation | Articles

Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy

Authors: Seay H, Putnam A, Cserny J, Posgai A, et al.

Published: Molecular Therapy: Methods & Clinical Development

2017 | Cryopreservation | Articles

Experimental evaluation of cryopreservative solutions to maintain in vitro and in vivo infectivity of P. berghei sporozoites

Authors: Singh N, Barnes S, Kennedy S, Adams J

Published: PLOS ONE

2017 | Cryopreservation | Articles

Generation of “Off-the-Shelf” Natural Killer Cells from Peripheral Blood Cell-Derived Induced Pluripotent Stem Cells

Authors: Zeng, Tang, Toh, Wang

Published: Stem Cell Reports

2017 | Cryopreservation | Articles

Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy

Authors: Hradilova N, Sadilkova L, Palata O, Mysikova D, et al.

Published: PLoS ONE

2017 | Cryopreservation | Articles

Human Mesenchymal Stem Cell Growth on Corning Denatured Collagen Dissolvable Microcarriers in a 5L Bioreactor 

Authors: Weber J., Romeo L., Dolley-Sonneville P.

Published: Corning Incorporated

2017 | Cryopreservation | Articles

Human Neural Stem Cell Therapy for Chronic Ischemic Stroke: Charting Progress From Laboratory to Patients

Authors: Sinden J, Hicks C, Stroemer P, Vishnubhatla I, Corteling R

Published: Stem Cells and Development

2017 | Cryopreservation | Articles

Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists

Authors: Raikar, Petersen, Spencer, Hassan, Sulchek, Morris, Flowers, Jeffery, Waller, Lee, Jagirdar, Staton

Published: Blood Advances

2017 | Cryopreservation | Articles

In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts

Authors: Kadota S, Pabon L, Reinecke H, Murry C

Published: Stem Cell Reports

2017 | Cryopreservation | Articles

Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment

Authors: Moussy A, Cosette J, Parmentier R, da Silva C, et al.

Published: PLoS Biology

2017 | Cryopreservation | Articles

Integrating Molecular Control to Improve Cryopreservation Outcome

Authors: Baust J, Snyder K, Van Buskirk R, Baust J

Published: Biopreservation and Biobanking

2017 | Cryopreservation | Articles

Intent-to-treat leukemia remission by CD19 CAR T cells of defined formulation and dose in children and young adults

Authors: Gardner R,  Finney O, Annesley C,  Brakke H,  et al.

Published: Blood

2017 | Cryopreservation | Articles

Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease

Authors: Rothe, Klassen, Huang, Rip, Turner, Khan, Abaoui, Sirrs, Au, Nagree, Rupar, Barber, Dworski, Auray-Blais, López-Vásquez, Schambach, Foley, Medin, Prokopishyn, Keating, Boutin, West

Published: Molecular Therapy: Methods & Clinical Development

2017 | Cryopreservation | Articles

Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34+ Hematopoietic Stem and Progenitor Cells

Authors: Chang K, Smith S, Sullivan T, Chen K, et al.

Published: Molecular Therapy: Methods & Clinical Development

2017 | Cryopreservation | Articles

Long-term In Vivo Monitoring of Adult-Derived Human Liver Stem/Progenitor Cells by Bioluminescence Imaging, Positron Emission Tomography, and Contrast-Enhanced Computed Tomography

Authors: Gregoire, Hsu, Goldman, Prigent, Deblandre, Dollet, Najimi, Ravau, Sokal, Larbanoix, Lombard, Simaeys, Bol

Published: Stem Cells and Development

2017 | Cryopreservation | Articles

Lym-1 Chimeric Antigen Receptor T Cells Exhibit Potent Anti Tumor Effects against B-Cell Lymphoma

Authors: Epstein, Zheng, Hu, Wolfe, Gonsalves, Ren, Khawli, Kaslow

Published: International Journal Of Molecular Sciences

2017 | Cryopreservation | Articles

Marker-free coselection for CRISPR-driven genome editing in human cells

Authors: Agudelo D, Duringer A, Bozoyan L, Huard C, et al.

Published: Nature Methods

2017 | Cryopreservation | Articles

Mutant Huntingtin Disrupts the Nuclear Pore Complex

Authors: Grima J, Daigle J. G, Arbez N, Cunningham K, et al.

Published: Neuron

2017 | Cryopreservation | Articles

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

Authors: Rao D, Gurish M, Marshall J, Slowikowski K, et al.

Published: Nature

2017 | Cryopreservation | Articles

Peripheral blood derived induced pluripotent stem cells (iPSCs) from a female with familial hypertrophic cardiomyopathy

Authors: Ross S, B., Fraser S, Bagnall R, Semsarian C

Published: Stem Cell Research

2017 | Cryopreservation | Articles

Preclinical Assessment of CD171-Directed CAR T-cell Adoptive Therapy for Childhood Neuroblastoma: CE7 Epitope Target Safety and Product Manufacturing Feasibility

Authors: Kunkele A, Taraseviciute A, Finn L, Johnson A, et al.

Published: Clinical Cancer Research

2017 | Cryopreservation | Articles

Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine Conjugated Antibody–Drug Conjugate Targeting 5T4

Authors: Hinrichs, Jovanovic, Chen, Harper, Huang, Fleming, Wetzel, Lloyd, Howard, d'Hooge, Breen, Dimasi, Tice, Mao, van Vlerken-Ysla, Toader, Hollingsworth, Marrero, Jalla, Marwood, Herbst, Korade, Rebelatto, Zhong, Lewis, Kamal, Strout, Hurt, Bannister, Xu

Published: Molecular Cancer Therapeutics

2017 | Cryopreservation | Articles

Prostaglandin E2 Indicates Therapeutic Efficacy of Mesenchymal Stem Cells in Experimental Traumatic Brain Injury

Authors: Kota D, Prabhakara K, Tolendano-Furman N, Bhattarai D, et al.

Published: Stem Cells

2017 | Cryopreservation | Articles

Regional Delivery of Chimeric Antigen Receptor– Engineered T Cells Effectively Targets HER2þ Breast Cancer Metastasis to the Brain

Authors: Ostberg, Princeman, Neman, Tilakawardane, Jandial, Jeang, Portnow, Aguilar, Forman, Murad, Brown, Park, Chang

Published: Clinical Cancer Research

2017 | Cryopreservation | Articles

Stem Cell Banking: Concepts and Protocols. Culturing and Cryobanking Human Neural Stem Cells

Authors: Crook, Tomaskovic-Crook

Published: Stem Cell Banking: Concepts and Protocols

2017 | Cryopreservation | Articles

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

Authors: Hookway C, Roberts B, Ludmann S, Amanda H, Mueller I, Tucker A, Yang R, Grancharova T, Horwitz A, Arakaki J, Rafelski S, Fuqua M, Gunawardane R, Nelson A

Published: Molecular Biology of the Cell

2017 | Cryopreservation | Articles

The Effects of Tacrolimus on T-Cell Proliferation Are Short-Lived: A Pilot Analysis of Immune Function Testing

Authors: S., M. H., Laskin, Furth, Reese, B. L., S. L., P. P. and Beier, Jiao, Akimova, U. H., J., T., Baluarte, Hancock, H. J., W. W., Amaral, Levine

Published: Transplant Direct

2017 | Cryopreservation | Articles

Tissue Engineering to Repair Diaphragmatic Defect in a Rat Model

Authors: Hetz, Li, Liao, Corkins, Choi, Hughes, Vojnits, Triolo, Xue, Johnson, Aroom, Moise, Meng, Lally, Pan, Cox

Published: Stem Cells International

2016 | Cryopreservation | Articles

A Rapid Cell Expansion Process for Production of Engineered Autologous CAR-T Cell Therapies

Authors: Lu T, Pugach O, Somerville R, Rosenberg S, et al.

Published: Human Gene Therapy Methods

2016 | Cryopreservation | Articles

A10.08 Detailed analysis of the effect of cryopreservation on the viability and cytokine release of human synovial tissue.

Authors: de Vries M, Broeren MGA, Bennink MB, et al.

Published: Annals of the Rheumatic Diseases

2016 | Cryopreservation | Articles

ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration (ALLSTAR) Trial: Rationale and Design

Authors: Povsic TJ, Chakravarty T, Smith RR, Makkar RR, Lima JA, Ascheim DD, Pogoda JM, Traverse JH, Marban L, Schatz R, Henry TD, DeMaria A, Francis GS

Published: Cell Transplantation

2016 | Cryopreservation | Articles

Cell freezing protocol optimized for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells

Authors: Sareen D, Milani P, Svendsen CN, Escalante-Chong R, Fraenkel E, Shelley BC, Patel-Murray NL, Xin X, Adam M, Mandefro B

Published: BioRxiv Epublication

2016 | Cryopreservation | Articles

Cryopreservation and Revival of Human Mesenchymal Stromal Cells

Authors: Chapter Authors: Mandana Haack-Sorensen, Annette Ekblond, Jens Kastrup. Senior Editor: John M. Walker. Edited by: Massimiliano Gnecchi

Published: Methods in Molecular Biology Series

2016 | Cryopreservation | Articles

Cryopreservation of Human Pluripotent Stem Cell-Derived Cardiomyocytes: Strategies, Challenges, and Future Directions

Authors: Preininger M, Singh M, Xu C

Published: Advances in Experimental Medicine and Biology

2016 | Cryopreservation | Articles

Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy

Authors: Gramlich OW, Burand AJ, Brown AJ, Deutsch RJ, Kuehn MH, Ankrum JA.

Published: Scientific Reports

2016 | Cryopreservation | Articles

Current approaches and future perspectives on strategies for the development of personalized tissue engineering therapies.

Authors: Neves LS, Rodrigues MT, Reis RL, Gomes ME

Published: Expert Review of Precision Medicine and Drug Development. Vol 1, Iss. 1, 2016

2016 | Cryopreservation | Articles

Designing a dendritic cell-based therapy for primary liver cancer

Authors: Curbishley SM, Blahova M, Adams DH

Published: MACS & more

2016 | Cryopreservation | Articles

Enhanced Immunosuppression of T Cells by Sustained Presentation of Bioactive Interferon-γ Within Three-Dimensional Mesenchymal Stem Cell Constructs.

Authors: Zimmermann JA, Hettiaratchi MH, McDevitt TC

Published: Stem Cells Translational Medicine

2016 | Cryopreservation | Articles

Episomal plasmid-based generation of an iPSC line from a 79-year-old individual carrying the APOE4/4 genotype: i11001

Authors: Zulfiqar S, Fritz B, Nieweg K

Published: Stem Cell Research

2016 | Cryopreservation | Articles

Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation

Authors: R. H., L. L., Guinan, Janec, Turka, E. C., K. J., L. A. and Markmann, Cole, Yuan, J., G. A., H., Wylie, Oppatt, W. H., J., Kelner, Brennan

Published: American Journal Of Transplantation

2016 | Cryopreservation | Articles

Fast and Efficient Neural Conversion of Human Hematopoietic Cells

Authors: Bruzos-Cidon C, Castano J, Torrecilla M, Sanchez-Pernaute R, Giorgetti A

Published: Current Protocols in Stem Cell Biology

2016 | Cryopreservation | Articles

Flexible insect cell platforms for fast production of pseudotyped virus-like particles

Authors: Bárbara Dias Fernandes

Published: University of Lisbon

2016 | Cryopreservation | Articles

Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons

Authors: Telezhkin V, Schnell C, Yarova P, Yung S, Cope E, et al.

Published: American Journal of Physiology - Cell Physiology

2016 | Cryopreservation | Articles

Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium

Authors: Broeren M, de Vries M, Bennink M, van Lent P, et al.

Published: PLoS ONE

2016 | Cryopreservation | Articles

Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques

Authors: Aliota M, Dudley D, Newman C, Mohr E, et al.

Published: PLoS Neglected Tropical Diseases

2016 | Cryopreservation | Articles

How transplant centers deal with the dextran shortage: recommendations for comparing alternatives

Authors: Regan D, Brady C, Armitage S, Freed B, Duffy M, Gass A, Spellman S, Kurtzberg J

Published: Transfusion

2016 | Cryopreservation | Articles

Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions

Authors: M., L., Slamecka, Kehl, Hoerstrup, J., D., S. P. and Weber, Salimova, Laurini, B., L., J., McClellan, Cinelli, S., P., van Kelle, Owen

Published: Cell Cycle

2016 | Cryopreservation | Articles

Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce

Authors: Herzog R, Nichols T, Su J, Zhang B, et al.

Published: Molecular Therapy

2016 | Cryopreservation | Articles

Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL

Authors: Wong C, Gidwaney N, Wang X, Urak R, Thomas S, Popplewell L, Chang W, Cooper L, Wagner J, Khaled S, Riddell S, Naranjo A, Siddiqi T, Brown C, Blanchard M, Budde L, Jensen M, Forman S, Mott M, Xu J, Norris A, Chang B

Published: Blood

2016 | Cryopreservation | Articles

Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells

Authors: DiGiusto D, Cannon P, Holmes M, Lijing L, et al.

Published: Molecular Therapy: Methods & Clinical Development

2016 | Cryopreservation | Articles

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

Authors: Brown C, Alizadeh D, Starr R, Weng L, et al.

Published: The New England Journal of Medicine

2016 | Cryopreservation | Articles

Relevance of flow cytometric enumberation of post-thaw leucocytes: influence of temperature during cell staining on viable cell recovery

Authors: Scharner D, Fritsch G, Trbojevic D, Frank N, Zipperer E, Dmytrus J, Printz D, Frech C, Worel N., Pichler H, Witt V, Geyeregger R

Published: Vox Sanguinis

2016 | Cryopreservation | Articles

Response to Intravenous Allogeneic Equine Cord Blood-Derived Mesenchymal Stromal Cells Administered from Chilled or Frozen State in Serum and Protein-Free Media.

Authors: Williams LB, Co C, Koenig JB, Tse C, Lindsay E, Koch TG

Published: Frontiers in Veterinary Science

2016 | Cryopreservation | Articles

Successful expansion of functional and stable regulatory T Cells for immunotherapy in liver transplantation

Authors: Safinia N, Vaikunthanathan T, Fraser H, Thirkell S, et al.

Published: Onotarget

2016 | Cryopreservation | Articles

The Cocoon® Platform Combined With the 4D-Nucleofector® LV Unit: A Non-viral Workflow for Modifying Primary T Cells

Authors: K., T., Hwa Neo, Daita, Schroeder, B., K., J., Bandapalle, Sei, Abraham, S., J., E., O’Connor, Zander, Shi, Y., J., M., Lin, Gleissner

Published: Lonza

2015 | Cryopreservation | Articles

A placebo-controlled randomised trial to assess the effect of TGF-ß1-expressing chondrocytes in patients with arthritis of the knee

Authors: Mont MA, Lee MC, Ha CW, Elmallah RK, Cherian JJ, Cho JJ, Kim TW, Bin SI

Published: The Bone & Joint Journal

2015 | Cryopreservation | Articles

A simple and efficient method for cryopreservation and recovery of viable Plasmodium vivax and P. falciparum sporozoites

Authors: Singh N, Barnes SJ, Jenwithisuk R, Sattabongkot J, Adams JH

Published: Parasitology International. Epub 8 Dec 2015

2015 | Cryopreservation | Articles

A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection of control virus replication after a limiting-dose heterologous SIV challenge.

Authors: Reynolds, Matthew R. ; Weiler, Andrea M.; Piaskowski, Shari M.; et al.

Published: Vaccine

2015 | Cryopreservation | Articles

Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation.

Authors: Fernandes P et al.

Published: Scientific Reports

2015 | Cryopreservation | Articles

Cryopreservation and Hypothermal Storage of Hematopoietic Stem Cells

Authors: AlMulhem, Norah

Published: University of Cincinnati, Allied Health Sciences: Transfusion and Transplantation Sciences

2015 | Cryopreservation | Articles

Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells

Authors: J Chai, V Chen, J Gold, J Ye, J Wu, P Shukla, D Hsu, G Hua, L Couture, D Chen, Z Lin, J Liu

Published: Stem Cell Research

2015 | Cryopreservation | Articles

Functionalizing Ascl1 with Novel Intracellular Protein Delivery Technology for Promoting Neuronal Differentiation of Human Induced Pluripotent Stem Cells

Authors: R. and Willerth, Robinson, S. M., M., Chapani, P., Styan, T., Vaidyanathan

Published: Stem Cell Reviews And Reports

2015 | Cryopreservation | Articles

Human Engineered Heart Muscles Engraft and Survive Long-Term in a Rodent Myocardial Infarction Model

Authors: Riegler J, Tiburcy M, Ebert A, Tzatzalos E, Raaz U, et al.

Published: Circulation Research

2015 | Cryopreservation | Articles

Human umbilical cord blood-derived mononuclear cells improve murine ventricular function upon intramyocardial delivery in right ventricular chronic pressure overload

Authors: Oommen S, Yamada S, Peral SC, Campbell KA, Bruinsma ES, Terzic A, Nelson TJ

Published: Stem Cell Research & Therapy

2015 | Cryopreservation | Articles

Method validation for automated isolation of viable peripheral blood mononuclear cells.

Authors: Hamot G, Ammerlaan W, Mathay C, Kofanova O, Betsou F.

Published: Biopreservation and Biobanking

2015 | Cryopreservation | Articles

Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy

Authors: Skopicki HA, Greene SJ, Sikora S, Epstein SE, Verkh L, Kim RJ, Tankovich NI, Quyyumi AA, Gheorghiade M, Cole RT, Butler J, Anderson AS, Wilcox JE

Published: Journal of Cardiovascular Medicine

2015 | Cryopreservation | Articles

Safety and Feasibility for Pediatric Cardiac Regeneration Using Epicardial Delivery of Autologous Umbilical Cord Blood-Derived Mononuclear Cells Established in a Porcine Model System.

Authors: Peral SC, Burkhart HM, Oommen S, Yamada S, et al.

Published: Stem Cells Translational Medicine

2015 | Cryopreservation | Articles

Sendai Virus-Based Reprogramming of Mesenchymal Stromal/Stem Cells from Umbilical Cord Wharton’s Jelly into Induced Pluripotent Stem Cells.

Authors: Miere, C., Devito, L., and Ilic, D.

Published: Methods In Molecular Biology

2015 | Cryopreservation | Articles

TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients.

Authors: Hossain DMS, Pal SK, Moreira D, et al.

Published: Clinical Cancer Research

2014 | Cryopreservation | Articles

 Measuring the Potency of a Stem Cell Therapeutic

Authors: Harper H, Rich I

Published: Stem Cell Protocols, Methods in Molecular Biology

2014 | Cryopreservation | Articles

Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy

Authors: Takayama K, Li D, Yee K, Minamino N, Marban L, Malliaras K, Dawkins JF, Makkar RR, Kanazawa H, Chowdhury S, Marban E., Tseliou E, Duong DT, Cheng K, Seinfeld J, Luthringer DJ, Middleton RC, Ho CS, Kharmakumar R

Published: PLoS ONE

2014 | Cryopreservation | Articles

Amnion-Derived Multipotent Progenitor Cells Inhibit Blood Monocyte Differentiation Into Mature Dendritic Cells

Authors: Banas R, Miller C, Guzik L, Zeevi A.

Published: Cell Transplantation

2014 | Cryopreservation | Articles

An alliance with Miltenyi Biotec in the fight for tolerance: A venture into no man's land.

Authors: Safinia N, Lombardi G, Lechler R.

Published: MACS & more

2014 | Cryopreservation | Articles

C-40 Cryobiology: Changing the face of regenerative medicine

Authors: White C, Benson K, Cherukuri P, Beals T.

Published: Cryobiology

2014 | Cryopreservation | Articles

Dendritic Cells Transfected with Adenoviral Vectors as Vaccines.

Authors: Senesac J, et al.

Published: Methods in Molecular Biology

2014 | Cryopreservation | Articles

Differentiation and expansion of hematopoietic precursor cells from bone-marrow derived CD34+ progenitors

Authors: Clinton J, Shapiro B.

Published: American Type Culture Collection (ATCC)

2014 | Cryopreservation | Articles

Direct Programming of Neural Progenitors into Medium Spiny Neurons by Transcription Factor Transfection

Authors: Geater, Charlene

Published: Cardiff University

2014 | Cryopreservation | Articles

Effective Cryopreservation and Recovery of Human Regulatory T Cells

Authors: Foussat A, Rietze R, Pottier E, et al.

Published: BioProcess International

2014 | Cryopreservation | Articles

Exome sequencing in single cells from the cerebrospinal fluid in multiple sclerosis

Authors: Kemppinen AK, Baker A, Liao W, et al.

Published: Multiple Sclerosis Journal

2014 | Cryopreservation | Articles

Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity.

Authors: Pan L, Jordan CT., Callahan KP, Jacob S, Minhajuddin M, Frontier A, Corbett C, Grever MR, Lagadinou ED, Lucas DM, Rossi RM, Kinghorn AD, Grose V, Liesveld JL, Balys MM, Becker MW

Published: Leukemia (28 February 2014)

2014 | Cryopreservation | Articles

High Yield Recovery of Equine Mesenchymal Stem Cells from Umbilical Cord Matrix/Wharton’s Jelly Using a Semi-automated Process

Authors: Nazari-Shafti, Bruno, Martinez, Coleman, Alt, McClure

Published: Stem Cell Protocols, Methods in Molecular Biology

2014 | Cryopreservation | Articles

Human-derived raw materials: controlled, consistent collection and cryopreservation enable successful manufacturing of cell-based products.

Authors: Ramos TV, Wang W, Okhovat J, McPherson G, Burger S.

Published: Cytotherapy

2014 | Cryopreservation | Articles

In-Depth Characterisation of Retinal Pigment Epithelium (RPE) Cells Derived from Human Induced Pluripotent Stem Cells (hiPSC).

Authors: Federlin M, Brandl C, Wetzel CH, Zimmermann SJ, Helbiq H, Milenkovic VM, Weber BH., Rosendahl SM, Grassmann F, Milenkovic A, Hehr U

Published: Neuromolecular Medicine

2014 | Cryopreservation | Articles

Insect Cell Line Development Using Flp-Mediated Cassette Exchange Technology.

Authors: A.P., Vidigal, Alves, J., P.M., Fernandes, F., Coroadinha, A.S., Teixeira

Published: Methods in Molecular Biology (Methods and Protocols)

2014 | Cryopreservation | Articles

Isolation and Expansion of Mesenchymal Stromal/Stem Cells from Umbilical Cord Under Chemically Defined Conditions

Authors: Badraiq H, Devito L, Ilic D.

Published: Methods in Molecular Biology

2014 | Cryopreservation | Articles

Mesenchymal Stem Cells for Regenerative Therapy: Optimization of Cell Preparation Protocols

Authors: Ikebe C, Suzuki K.

Published: BioMed Research International

2014 | Cryopreservation | Articles

Osteoblastic VEGF Coordinates Remodeling of the Hematopoietic Stem Cell Niche 

Authors: Smith, Calvi

Published: PhD Thesis, Department of Pathology and Laboratory Medicine, University of Rochester

2014 | Cryopreservation | Articles

PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation.

Authors: Kolodziej, S. et al.

Published: Nature Communications

2014 | Cryopreservation | Articles

Phenotypic Characteristics of Mucosally Transmitted Hiv-1

Authors: Parrish, Nicholas F.

Published: University of Pennsylvania

2014 | Cryopreservation | Articles

Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells

Authors: Kim K, Cho J, Feng Q, Brooks J, Lu S, Shabrani N, Li F, Lanza R., Thon, Luo C, JN, Kimbrel EA, Huo H, Want J, Thiel A, Kim K, Machlus KR, Italiano J

Published: Stem Cell Reports

2014 | Cryopreservation | Articles

Selective Activity of the Histone Deacetylase Inhibitor AR-42 against Leukemia Stem Cells: A Novel Potential Strategy in Acute Myelogenous Leukemia.

Authors: Steidl U, Guzman ML, Abdel-Wahab O, Yang N, Levine RL, Sharma KK, Marcucci G, Balys M, Roboz GJ, Corbett CA, Hassane DC., Jordan CT, Becker MW

Published: Molelcular Cancer Therapeutics

2014 | Cryopreservation | Articles

Standardized cryopreservation of human primary cells

Authors: Ramos TV, Mathew AJ, Thompson ML, Ehrhardt RO.

Published: Current Protocalls in Cell Biology

2014 | Cryopreservation | Articles

Viable Mononuclear Cell Stability Study for Implementation in a Proficiency Testing Program: Impact of Shipment Conditions

Authors: Kofanova OA, Davis K, Glazer B, De Souza Y, Kessler J, Betsou F, ISBER Biospecimen Science Working Group

Published: Biopreservation and Biobanking

2013 | Cryopreservation | Articles

An Optimized Multi-parameter Flow Cytometry Protocol for Human T Regulatory Cell Analysis on Fresh and Viably Frozen Cells, Correlation with Epigenetic Analysis, and Comparison of Cord and Adult Blood.

Authors: Nettenstrom L, Alderson K, Raschke E.E, Evans MD, Sondel P.M, Olek S, Seroogy S.M.

Published: Journal of Immunological Methods

2013 | Cryopreservation | Articles

BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

Authors: Lagadinou ED, Sach A, Callahan K, Rossi RM, Neering SJ, et al.

Published: Science Direct

2013 | Cryopreservation | Articles

Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation.

Authors: Putnam AL, Safinia N, et al.

Published: American Journal of Transplantation

2013 | Cryopreservation | Articles

Controlled-Rate Freezing of Cells During Ultra Cold Transit.

Authors: Hamy F.

Published: Fisher BioServices, Part of Thermo Fisher Scientific

2013 | Cryopreservation | Articles

Downstream Technology Landscape for Large-Scale Therapeutic Cell Processing.

Authors: Pattasseril J, Varadaraju H, Lock L, Rowley J.A.

Published: BioProcess International

2013 | Cryopreservation | Articles

Human Embryonic Stem Cell Derived Mesenchymal Progenitors Express Cardiac Markers but Do Not Form Contractile Cardiomyocytes

Authors: J., Raynaud, Elefanty, C. M., A. G., Halabi, Stanley, N., E. G. and Rafii, Elliott, A., D. A., Pasquier

Published: PLOS ONE

2013 | Cryopreservation | Articles

Melanoma immunotherapy using mature DCs expressing the constitutive proteasome.

Authors: Dannull J, Haley NR, Archer G, et al.

Published: Journal of Clinical Investigation

2013 | Cryopreservation | Articles

Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling.

Authors: Michaud NR, Wang Y, McEachern K, et al.

Published: Mol Cancer Ther

2013 | Cryopreservation | Articles

Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells.

Authors: Pei S, Minhajuddin M, Callahan KP, et al.

Published: J Biol Chem

2013 | Cryopreservation | Articles

Validation of Contrast-Enhanced MRI to Monitor Regenerative Efficacy after Cell Therapy in a Porcine Model of Convalescent Myocardial Infarction

Authors: A., K., R., M., Malliaras, Valle, Seinfeld, Li, Cheng, K., I., J., D., K., Smith, Chowdhury, Tseliou, Marban, Luthringer, R. R., S., E., L. and Marban, D., Kanazawa, Makkar, Dawkins, E., Ho, C., H., R. R., J. F., Blusztajn, Yee, Dharmakumar, Kreke

Published: Circulation

2012 | Cryopreservation | Articles

Bioartificial Renal Epithelial Cell System (BRECS): A Compact, Cryopreservable Extracorporeal Renal Replacement Device.

Authors: Buffington D.A, Pino CJ, Chen L, Westover A.J, Hageman G, Humes H.D.

Published: Cell Medicine

2012 | Cryopreservation | Articles

Bioprocessing of Cryopreservation for Large-Scale Banking of Human Pluripotent Stem Cells.

Authors: Li Y, Ma T.

Published: BioResearch Open Access

2012 | Cryopreservation | Articles

Cryopreservation of adenovirus-transfected dendritic cells (DCs) for clinical use.

Authors: Pirruccello SM, Gülen D, Talmadge JE., Maas S, Julius H, Warkentin P, Britton H, Younos I, Senesac J

Published: International Immunopharmacology

2012 | Cryopreservation | Articles

Cryopreservation of umbilical cord blood with a novel freezing solution that mimics intracellular ionic composition.

Authors: Reems J., Nicoud IA, Clarke DM, Taber G, Stolowski KM, Roberge SE, Song MK, Mathew AJ

Published: Transfusion.

2012 | Cryopreservation | Articles

Evaluation of Bone Marrow-Derived MSC after Cryopreservation and Hypothermic Storage in Clinically Safe Medium.

Authors: Ginis I, Grinblat B, Shirvan MH.

Published: Tissue Engineering Part C Methods

2012 | Cryopreservation | Articles

Evaluation of Bone Marrow-Derived MSC after Cryopreservation and Hypothermic Storage in Clinically Safe Medium.

Authors: Ginis I, Grinblat B, Shirvan MH.

Published: Tissue Engineering Part C: Methods

2012 | Cryopreservation | Articles

Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia.

Authors: Frisch B.J, Ashton J.M, Xing L, Becker M.W, Jordan C.T, Calvi L.M.

Published: Blood

2012 | Cryopreservation | Articles

Generation of human induced pluripotent stem cells from urine samples.

Authors: Zhang Y, Esteban M.A., Zhou T, Zhuang Q, Benda C, Li Y, Dunzinger S, Bao X, Huang Y, Tse H, Ho J.C, Grillari J, Yang J, Grillari-Voglauer R, Wang Y, Pei D

Published: Nature Protocols

2012 | Cryopreservation | Articles

Hyaluronan-Supplemented Buffers Preserve Adhesion Mechanisms Facilitating Cryopreservation of Human Hepatic Stem/Progenitor Cells.

Authors: Turner R, Mendel G, Wauthier E, Barbier C, Reid LM.

Published: Cell Transplantation

2012 | Cryopreservation | Articles

Improve Process Uniformity and Cell Viability in Cryopreservation.

Authors: Zhou Y, Fowler Z, Cheng A, Sever R.

Published: BioProcess International

2012 | Cryopreservation | Articles

Optimized Processing of Growth Factor Mobilized Peripheral Blood CD34+ Products by Counterflow Centrifugal Elutriation.

Authors: Ahmed A, Tran C, Digiusto D., Torres-Coronado M, Gardner A, Gu A, Vu H, Rao A, Cao IF

Published: Stem Cells Translational Medicine

2012 | Cryopreservation | Articles

Phenotypic and Functional Attributes of Lentivirus-modified CD19-specific Human CD8+ Central Memory T Cells Manufactured at Clinical Scale.

Authors: B, Wang X, Ostberg J.R, Naranjo A, Riddell SR, Brown C.E, Forman SJ, Bautista C, Jensen M.C., Wong C.W, Chang W, Aguilar

Published: Journal of Immunotherapy

2012 | Cryopreservation | Articles

Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers.

Authors: Bachellier P, Alexandre E, Heyd B, Baze A, Weber J, Parmentier C, Richert L., Desbans C, Pekthong D, Gerin B, Wack C

Published: Xenobiotica

2011 | Cryopreservation | Articles

A Synthetic, Xeno-Free Peptide Surface for Expansion and Directed Differentiation of Human Induced Pluripotent Stem Cells

Authors: Jin S, Yao H, Weber JL, Melkoumian ZK, Ye K.

Published: PLoS ONE

2011 | Cryopreservation | Articles

Affinity-Based Proteomics Reveal Cancer-Specific Networks Coordinated by Hsp90

Authors: Guzman, Beebe, Alpaugh, Moulick, Nimer, Perna, Gross, Ahn, Melnick, Hatzi, Pillarsetty, Zong, Neckers, Vu, Ku, Rodina, Chiosis, Zhao, Lewis, Cerchietti, Zatorska, Larson, Levine, DaGama, Taldone, Erdjument-Bromage, Caldas-Lopes, Smith-Jones

Published: Nature Chemical Biology

2011 | Cryopreservation | Articles

Development of an insect cell factory for the production of complex biopharmaceuticals using a synthetic biology approach

Authors: João Miguel Nunes Vidigal

Published: University of Lisbon

2011 | Cryopreservation | Articles

Improved Post-Thaw Stability Validation of Peripheral Blood Cell Products Utilizing the Intracellular-Like Cryostor Cryopreservation Solution, and Preliminary Results of Clinical Application.

Authors: Fritsch G, Witt V, Matthes S, Dworzak M, Artwohl M, Clarke D, Mathew AJ.

Published: Biology of Blood and Marrow Transplantation. February 2011; Volume 17, Issue 2, S210-S211.

2011 | Cryopreservation | Articles

Methods for the Derivation and Use of Cardiomyocytes from Human Pluripotent Stem Cells Methods.

Authors: Zhu WZ, Van Biber B, Laflamme MA.

Published: Mol Biol. Author manuscript

2011 | Cryopreservation | Articles

Optimizing Cryopreservation for Therapeutic Cells.

Authors: Rios M.

Published: BioProcess International

2011 | Cryopreservation | Articles

Packaging Considerations for Biopreservation

Authors: Erik J. Woods and Sreedhar Thirumala.

Published: Transfusion Medicine and Hemotherapy

2011 | Cryopreservation | Articles

Pooled peripheral blood mononuclear cells provide an optimized cellular substrate for human immunodeficiency virus Type 1 isolation during acute infection.

Authors: Lai-Hipp C, Goldberg T, Scott E, Ziman A, Vyas G.

Published: Transfusion

2011 | Cryopreservation | Articles

Porcine Intervertebral Disc Repair Using Allogeneic Juvenile Articular Chondrocytes or Mesenchymal Stem Cells.

Authors: Acosta FL, Metz L, Adkisson HD, et al.

Published: Tissue Engineering Part A. 2011;17(23-24):3045-3055.

2010 | Cryopreservation | Articles

(2010) A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations.

Authors: Hessel A, Schwendinger M, Fritz D, Coulibaly S, Holzer GW, et al.

Published: PLoS ONE

2010 | Cryopreservation | Articles

Alginate Encapsulation as a Novel Strategy for the Cryopreservation of Neurospheres.

Authors: Malpique R, Osório LM, Ferreira DS, Ehrhart F, Brito C, Zimmermann H, Alves PM.

Published: Tissue Eng Part C Methods

2010 | Cryopreservation | Articles

Amnion Epithelial Cell Isolation and Characterization for Clinical Use.

Authors: Murphy S, Rosli S, Acharya R, Mathias L, Lim R, Wallace E, Jenkin G.

Published: Current Protocols in Stem Cell Biology

2010 | Cryopreservation | Articles

Effect of cryopreservation and in vitro culture of bovine fibroblasts on histone acetylation levels and in vitro development of hand-made cloned embryos

Authors: Chacon L, Gomez M, Jenkins J, Leibo S, Wirtu G, Dresser B, Pope C

Published: Zygote

2010 | Cryopreservation | Articles

I’m Losing Cell Viability and Function at Different Points in My Process, and I Don’t Know Why!

Authors: Mathew, A.J.

Published: BioProcess International

2010 | Cryopreservation | Articles

Juvenile Chondorcytes May Facilitate Disc Repair

Authors: Kim AJ, Adkisson HD, Wendland M, Seyedin M, Berven S, Lotz JC.

Published: The Open Tissue Engineering and Regenerative Medicine Journal

2010 | Cryopreservation | Articles

Regulatory T cell expression of CLA or a4b7 and skin or gut acute GVHD outcomes

Authors: Engelhardt BG, Jagasia M, Savani BN, Bratcher NL, et al.

Published: Bone Marrow Transplantation

2009 | Cryopreservation | Articles

Clinical Grade Adult Stem Cell Banking.

Authors: Thirumala S, Goebel WS, Woods EJ.

Published: Organogenesis

2009 | Cryopreservation | Articles

Cryopreservation of Adherent Cells: Strategies to Improve Cell Viability and Function after Thawing.

Authors: Malpique R, Ehrhart F, Katsen-Globa A, Zimmermann H, Alves PM.

Published: Tissue Engineering Part C Methods

2009 | Cryopreservation | Articles

Improved post-thaw recovery of peripheral blood stem/progenitor cells using a novel intracellular-like cryopreservation solution.

Authors: Clarke DM, Yadock DJ, Nicoud IB, Mathew AJ, Heimfeld S.

Published: Cytotherapy

2009 | Cryopreservation | Articles

Infection with “Escaped” Virus Variants Impairs Control of Simian Immunodeficiency Virus SIVmac239.

Authors: Klimentidis YC, O’Connor DH, Valentine LE, Lank SM, Allison DB, Loffredo JT, Wiseman RW, Watkins DI., Bean AT, Weinfurter JT, León EJ, May GE, MacNair CE, Rakasz EG, Beal DR, Wilson NA, Piaskowski SM, Friedrich TC

Published: Journal of Virology

2009 | Cryopreservation | Articles

Interleukin (IL)-6 Modulates Transforming Growth Factor-β Expression in Skin and Dermal Fibroblasts from IL-6-Deficient Mice.

Authors: Luckett-Chastain LR, Gallucci RM.

Published: British Journal of Dermatology

2009 | Cryopreservation | Articles

Production of bovine cloned embryos with donor cells frozen at a slow cooling rate in a conventional freezer (−20 °C)

Authors: Chacon L, Gomez M, Jenkins J, Leibo S, Wirtu G, Dresser B, Pope C

Published: Zygote

2009 | Cryopreservation | Articles

Viability of the Human Adenocarcinoma Cell Line Caco-2: Influence of Cryoprotectant, Freezing Rate, and Storage Temperature.

Authors: Güll I, Alves PM, Gabor F, Wirth M.

Published: Scientia Pharmaceutica

2008 | Cryopreservation | Articles

Collection, Cryopreservation, and Characterization of Human Dental Pulp–Derived Mesenchymal Stem Cells for Banking and Clinical Use.

Authors: Woods EJ, Perry BC, Goebel WS., Zhou D, Wu X, Yang FC, Byers MA, Chu G, Hockema JJ

Published: Tissue Engineering Part C: Methods

2008 | Cryopreservation | Articles

Isolation, Characterization, and Differentiation of Human Umbilical Cord Perivascular Cells (HUCPVCs).

Authors: Ennis J, Sarugaser R, Gomez A, Baksh D, Davies JE.

Published: Methods in Cell Biology

2007 | Cryopreservation | Articles

Activation of Mitochondrial-Associated Apoptosis Contributes to Cryopreservation Failure

Authors: R. G., Baust, Baust, J. M., J. G., Vogel, M. J., Snyder, K. K., Van Buskirk

Published: Cell Preservation Technology

2006 | Cryopreservation | Articles

Involvement of the Cysteine Protease Calpain Family in Cell Death After Cryopreservation.

Authors: Robilotto AT, Baust JM, Van Buskirk R, Baust JG.

Published: Cell Preservation Technology

2006 | Cryopreservation | Articles

Methods for the Effective Preservation of Cell and Tissue Samples 

Authors: Mathew, AJ, Snyder, KK, Baust, JM

Published: BioTechniques

2006 | Cryopreservation | Articles

Navigating the Postpreservation Viability Fog.

Authors: Van Buskirk RG, Snyder KK, Mathew AJ, Baust JG, Baust JM.

Published: GEN

2006 | Cryopreservation | Articles

Novel Cryoprotectant Significantly Improves the Post-thaw Recovery and Quality of HSC from CB.

Authors: Stylianou, J., Vowels, M. and Hadfield, K.

Published: Cytotherapy

2006 | Cryopreservation | Articles

Steps to Improving Cryopreservation Outcome: Understanding key factors influencing efficacy.

Authors: Baust JM, Snyder KK, Mathew, AJ, Van Buskirk RG., Baust, John G.

Published: Bioscience Technology

2005 | Cryopreservation | Articles

Advances in Media for Cryopreservation and Hypothermic Storage.

Authors: Baust, J.M.

Published: BioProcess International Supplement

2005 | Cryopreservation | Articles

Cryopreservation – It’s Not Just About Cell Yield.

Authors: Van Buskirk RG, Snyder KK, Baust JG, Mathew AJ, Baust, JM.

Published: BioProcessing International

2005 | Cryopreservation | Articles

Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function.

Authors: Sosef MN, Baust JM, Sugimachi K, Fowler A, Tompkins RG, Toner M.

Published: Annals of Surgery

2004 | Cryopreservation | Articles

Analysis of the functional integrity of cryopreserved human liver cells including xenografting in immunodeficient mice to address suitability for clinical applications.

Authors: R.K., R., Cho, Wang, Gupta, J.J., R., S., Joseph, Ludlow, B., J.W., Sappal, Furth, B.S., M.E., Giri, Susick

Published: Liver International

2004 | Cryopreservation | Articles

Biological Packaging for the Global Cell and Tissue Therapy Markets.

Authors: Snyder KK, Van Buskirk RG, Mathew AJ, Baust JG, Baust JM.

Published: BioProcessing Journal

2004 | Cryopreservation | Articles

Hypothermic Storage and Cryopreservation – The Issues of Successful Short-term and Long-term preservation of cells and tissues.

Authors: Van Buskirk RG, Baust JM, Snyder KK, Mathew AJ, Baust JG.

Published: Bioprocessing International

2004 | Cryopreservation | Articles

Long-Term Function of Cryopreserved Rat Hepatocytes in a Coculture System.

Authors: Sugimachi K., Sosef MN, Baust JM, Fowler A, Tompkins RG, Toner M.

Published: Cell Transplantation

2002 | Cryopreservation | Articles

Gene Activation of the Apoptotic Caspase Cascade Following Cryogenic Storage.

Authors: Baust JM, Van Buskirk RG, Baust JG.

Published: Cell Preservation Technology

2002 | Cryopreservation | Articles

Modulation of the cryopreservation cap: elevated survival with reduced dimethyl sulfoxide concentration.

Authors: Baust JM, Van Buskirk RG, Baust JG.

Published: Cryobiology

2002 | Cryopreservation | Articles

Molecular Mechanisms of Cellular Demise Associated with Cryopreservation Failure.

Authors: Baust JM.

Published: Cell Preservation Technology

2001 | Cryopreservation | Articles

A molecular basis of cryopreservation failure and its modulation to improve cell survival.

Authors: Baust JM, Vogel MJ, Van Buskirk RG, Baust JG.

Published: Cell Transplantation

2001 | Cryopreservation | Articles

Islet cryopreservation using intracellular preservation solutions.

Authors: Lakey JR, Rajotte RV, Fedorow CA, Taylor MJ.

Published: Cell Transplantation

2000 | Cryopreservation | Articles

Cell viability improves following inhibition of cryopreservation-induced apoptosis.

Authors: Baust JM, Van Buskirk RG, Baust JG.

Published: In Vitro Cellular and Developmental Biology

1999 | Cryopreservation | Articles

Cryopreservation of an engineered skin equivalent: The apoptosis paradigm.

Authors: Baust, JM, Van Buskirk RG, Baust JG.

Published: Journal of the American Society of Mechanical Engineers

October 2023 | Cryopreservation | Articles

A Paradigm Shift in Cryopreservation: Molecular-Based Advances to Improve Outcome

Authors: Baust JM, Baust JG

Published: CryoGenic Engineering; Fifty Years of Progress

October 2023 | Cryopreservation | Articles

ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia

Authors: Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, et al.

Published: Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678. Epub 2016 Oct 10.

October 2023 | Cryopreservation | Articles

CD133 and ALDH1 as Prospective Markers for Cancer Stem Cells in Ileal Carcinoids

Authors: Tobias Hofving.

October 2023 | Cryopreservation | Articles

Surgical meshes coated with mesenchymal stem cells provide an anti-inflammatory environment by a M2 macrophage polarization.

Authors: Blázquez R, Sánchez-Margallo FM, Alvarez V, Uson A, Casado JG

Published: Acta Biomaterialia

October 2023 | Cryopreservation | Articles

Transplantation of Defined Populations of Differentiated Humas Neural Stem Cell Progeny

Authors: Deleyrolle LP, Fortin JM, Reynolds BA, Azari H, Zheng T, Darioosh RP, Schmoll, ME, Vedam-Mai V

Published: Scentific Reports

October 2023 | Cryopreservation | Articles

Widespread Myocardial Delivery of Heart-Derived Stem Cells by Nonocclusive Triple-Vessel Intracoronary Infusion in Porcine Ischemic Cardiomyopathy: Superior Attenuation of Adverse Remodeling Documented by Magnetic Resonance Imaging and Histology

Authors: Valle J, Tseliou E, Marban L, Kanazawa H, Kar S, Dawkins J, Makkar R, Gallet R, Marbán E, Kreke M, Smith R, Middleton R

Published: PLoS One

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